RECRUITING

Investigating the Effects of Beef Consumption on Cognitive and Brain Health

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The goal of this clinical trial is to learn if eating more beef will lead to better cognition and a healthier brain in younger adults. The main questions it aims to answer are: * Does eating more beef lead to higher scores on cognitive tests and better quality of life? * Does eating more beef lead to better brain function? Researchers will compare participants in the experimental group (participants who will eat 25 ounces of beef every week during the dietary intervention) to control participants (participants who will eat 5 ounces of beef every week during the dietary intervention). Participants will: * Be instructed to prepare and consume ready-to-eat beef meals along with their regular diet and not eat any more beef other than what they are given * Visit the study facilities once every week to pick up ready-to-eat beef meals; and complete a brief survey every week to track their consumption of the provided beef meals, and a dietary survey every 4 weeks * Visit the study facilities before and after the 12-week of intervention period for researchers to study them

Official Title

Understanding the Cognitive and Brain Health Effects of Increasing Beef Consumption in Young Adults

Quick Facts

Study Start:2025-08
Study Completion:2026-12
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06690892

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:19 Years to 24 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT
Inclusion CriteriaExclusion Criteria
  1. * Provision of signed and dated informed consent form
  2. * Stated willingness to comply with all study procedures and lifestyle considerations and availability for the duration of the study
  3. * Males and females; Age 19-24
  4. * Willingness to adhere to the ready-to-eat beef intervention regimen
  5. * Enrolled at University of Nebraska-Lincoln
  6. * BMI between 18.5 and 39.9
  7. * Not pregnant or nursing
  8. * No history of cognitive or metabolic diseases indicated by diagnosis, including neurodegenerative disease, stroke, Type 1 and 2 diabetes, metabolic syndrome, cardiovascular disease, liver disease, kidney disease, and cancer
  9. * No history of eating or anxiety disorders
  10. * Willing to discontinue dietary supplement use throughout the duration of the study, if they are consuming supplement at the time of the registration
  11. * No known contraindication to MRI scans as determined by the MRI screening survey questions
  1. * Current use of medications that may affect their responses to dietary intervention, such as amphetamines, antidepressants, anti-diabetic medications, laxatives, antibiotics, statins and diuretics.
  2. * Known intolerance or allergy to beef
  3. * Current use of nicotine products, including vaping
  4. * Previous use of nicotine products, including vaping, within the recent 6 months at the time of pre-screening

Contacts and Locations

Study Contact

Aron Barbey, PhD
CONTACT
402-472-0168
abarbey2@unl.edu
Douglas Schultz, PhD
CONTACT
402-472-1843
dhschultz@unl.edu

Principal Investigator

Aron Barbey, PhD
PRINCIPAL_INVESTIGATOR
University of Nebraska Lincoln

Study Locations (Sites)

University of Nebraska-Lincoln
Lincoln, Nebraska, 68588
United States

Collaborators and Investigators

Sponsor: University of Nebraska Lincoln

  • Aron Barbey, PhD, PRINCIPAL_INVESTIGATOR, University of Nebraska Lincoln

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2025-08
Study Completion Date2026-12

Study Record Updates

Study Start Date2025-08
Study Completion Date2026-12

Terms related to this study

Keywords Provided by Researchers

  • beef consumption
  • beef dietary intervention
  • brain health
  • cognitive health

Additional Relevant MeSH Terms

  • Dietary Intervention
  • Dietary Proteins
  • Dietary Assessment
  • Cognitive Ability, General