Next-Generation Photon-Counting CT Technology: Development and Clinical Evaluation

Description

This project aims to develop and evaluate a next-generation photon-counting CT prototype, and assess whether next-generation photon-counting CT--which enables reduced radiation dose, high spatial resolution, and spectral imaging--would facilitate improved diagnostic performance for abdominal, cardiothoracic, musculoskeletal, and neuroimaging.

Conditions

Radiation Protection, Image Enhancement

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Study Overview

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Study Details

Study overview

This project aims to develop and evaluate a next-generation photon-counting CT prototype, and assess whether next-generation photon-counting CT--which enables reduced radiation dose, high spatial resolution, and spectral imaging--would facilitate improved diagnostic performance for abdominal, cardiothoracic, musculoskeletal, and neuroimaging.

Next-Generation Photon-Counting CT Technology: Development and Clinical Evaluation

Next-Generation Photon-Counting CT Technology: Development and Clinical Evaluation

Condition
Radiation Protection
Intervention / Treatment

-

Contacts and Locations

Philadelphia

University of Pennsylvania - Center for Advanced Computed Tomography Imaging Services (CACTIS), Philadelphia, Pennsylvania, United States, 19104

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Age 18 to 89.
  • * Participants must be informed of the investigational nature of this study and be willing to provide written informed consent and participate in this study in accordance with institutional and federal guidelines prior to study-specific procedures.
  • * Not pregnant (based on attestation)
  • * Pregnant women will not be included. All females of childbearing potential must attest that they are not pregnant before CT imaging.
  • * Participants with a known contrast allergy.
  • * Any current medical condition, illness, or disorder, as assessed by medical record review and/or self-reported, that is considered by a physician investigator to be a condition that could compromise participant safety or successful participation in the study.

Ages Eligible for Study

18 Years to 89 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

University of Pennsylvania,

Peter B Noel, PhD, PRINCIPAL_INVESTIGATOR, UPENN Radiology

Study Record Dates

2026-11-30