Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
For general information about clinical research, read Learn About Studies.
Eligibility Criteria
- * 21-64 years old and healthy;
- * Confirmed by genetic test to be a CYP2C19 normal, rapid, or ultra-rapid metabolizer;
- * Not taking any medications (prescription and non-prescription, including clopidogrel) or dietary supplements/botanical products known to alter the pharmacokinetics of cannabis and/or clopidogrel;
- * Have taken hemp or cannabis (in any form) before and tolerated it well;
- * Willing to abstain from consuming dietary supplements/botanical products and citrus juices for the duration of the study;
- * Willing to abstain from cannabis/marijuana, hemp, THC- and/or CBD-containing products for several weeks;
- * Willing to abstain from consuming caffeinated beverages or other caffeine-containing products the evening before and morning of any inpatient day;
- * Willing to abstain from consuming alcoholic beverages for one day prior to any inpatient day;
- * Willing to use a secondary method of birth control that does not include the introduction or discontinuance of hormonal-based birth control (such as abstinence, copper IUD, or condoms), continuing for 1 week after completing the study;
- * Have the ability to and are willing to comply with the requirements of the study;
- * Geographically located within a 40-mile radius of Spokane and have the time to participate and;
- * Can read and speak English
- * Under the age of 21 or over the age of 64;
- * Any major illness;
- * Pregnant or nursing;
- * History of allergy or intolerance to cannabis or clopidogrel;
- * Taking concomitant medications, both prescription and non-prescription (including clopidogrel) or dietary supplements/botanical products known to alter the pharmacokinetics of cannabis and/or clopidogrel;
- * Never taken cannabis (in any form) before;
- * Presence of a condition or abnormality that, in the opinion of the Investigator, would compromise participant safety or the quality of the data;
- * Currently using or have recently used drugs or other illicit substances for recreational purposes;
- * Have used cannabis/marijuana, hemp, THC- and/or CBD-containing products within the last 4 weeks;
- * Have an out-of-range clinical laboratory value such that the study physician considers participation in the study a health risk, or;
- * Unable to read and speak English
Ages Eligible for Study
21 Years to 64 Years
Sexes Eligible for Study
ALL
Accepts Healthy Volunteers
Yes