Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
For general information about clinical research, read Learn About Studies.
Eligibility Criteria
- * Between 18-64 years old and healthy
- * Not taking any medications (prescription and non-prescription) or dietary/herbal supplements that can interfere with study drug pharmacokinetics
- * Willing to abstain from consuming dietary/herbal supplements and citrus juices for several weeks
- * Willing to abstain from cannabis/marijuana, hemp, and THC- and CBD-containing products for several weeks
- * Willing to abstain from consuming caffeinated beverages or other caffeine-containing products the evening before and the morning of the first day of each study arm
- * Willing to abstain from consuming any alcoholic beverages for at least 1 day prior to any study day and during the study day
- * Willing to use a secondary method of birth control that does not include the introduction or discontinuance of hormonal-based birth control (such as abstinence, copper IUD, or condoms). Specifically, regardless of the use hormonal-based birth control, a non-hormonal method should be used for the duration of the study and for three weeks following cessation of participation.
- * Willing to abstain from consuming oregano (as a food additive or otherwise) for the duration of the study
- * Geographically located within a 40-mile radius of Spokane and have the time to participate
- * Under 18 or over 64 years old
- * Taking medications or dietary/herbal supplements that can interfere with study drug pharmacokinetics
- * Have a major illness
- * Taking medication/supplements for a mineral deficiency
- * History of intolerance or allergy to oregano or any of the cocktail drugs (caffeine, dextromethorphan, losartan, midazolam, and omeprazole)
- * Use of cannabis/marijuana, hemp, and CBD- and/or THC-containing products within the last month
- * Currently using drugs or illicit substances for recreational purposes
- * Pregnant or nursing
- * Geographically located outside the 40-mile radius of Spokane and do not have the time to participate
- * Cannot read and speak English
Ages Eligible for Study
18 Years to 64 Years
Sexes Eligible for Study
ALL
Accepts Healthy Volunteers
Yes