RECRUITING

Neuroscience of Psychotherapy for Depression

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The goal of this study is to learn the extent to which client-therapist brain activity may synchronize during a psychosocial intervention for depression symptoms. The study will compare behavioral activation, a client-centered type of cognitive-behavioral therapy, to psychoeducation which delivers information on strategies to recover from depression symptoms. Participants will answer questions about their mental and physical health, attend one psychosocial intervention session receiving either Behavioral Activation or Psychoeducation with simultaneous brain activity measurement and complete follow up surveys two weeks and one month following the intervention.

Official Title

Interbrain Synchronization of the Therapist-Client Dyad in Psychotherapy: Pilot EEG Study in Students With Mild-Moderate Depression Symptoms

Quick Facts

Study Start:2025-04-11
Study Completion:2025-10-31
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06696001

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 30 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT
Inclusion CriteriaExclusion Criteria
  1. Age 18 years or older
  2. Willing and able to provide informed consent
  3. Able to understand and follow study procedures
  4. Stable medical condition
  1. Pregnancy or breastfeeding
  2. Severe psychiatric disorders
  3. Active substance abuse
  4. Unstable medical conditions
  5. Inability to comply with study requirements

Contacts and Locations

Study Contact

Flavio Frohlich
CONTACT
(919) 966-4584
flavio_frohlich@med.unc.edu
Zachary Stewart
CONTACT
zachary_stewart@med.unc.edu

Principal Investigator

Flavio Frohlich
PRINCIPAL_INVESTIGATOR
Carolina Center for Neurostimulation

Study Locations (Sites)

Carolina Center for Neurostimulation
Chapel Hill, North Carolina, 27516
United States

Collaborators and Investigators

Sponsor: University of North Carolina, Chapel Hill

  • Flavio Frohlich, PRINCIPAL_INVESTIGATOR, Carolina Center for Neurostimulation

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2025-04-11
Study Completion Date2025-10-31

Study Record Updates

Study Start Date2025-04-11
Study Completion Date2025-10-31

Terms related to this study

Keywords Provided by Researchers

  • EEG
  • Hyperscanning
  • Therapeutic Alliance
  • Psychoeducation
  • behavioral activation

Additional Relevant MeSH Terms

  • Depression