Cranial Ultrasound for Point of Care Intracranial Pathology Detection in Pediatrics

Description

To improve patient selection for head CT, a safe and high sensitivity screening neuroimaging modality is needed. Currently many clinicians must make treatment decisions based solely on the patients clinical exam, which has low sensitivity and specificity and low inter-rater reliability. This study is being done to learn more about B-mode cranial point-of-care ultrasound (cPOCUS). Ultrasound has several advantages. It is a safe, non- invasive, low-cost, fast and portable bedside tool without ionizing radiation exposure.

Conditions

Traumatic Brain Injury

Study Overview

Study Details

Study overview

To improve patient selection for head CT, a safe and high sensitivity screening neuroimaging modality is needed. Currently many clinicians must make treatment decisions based solely on the patients clinical exam, which has low sensitivity and specificity and low inter-rater reliability. This study is being done to learn more about B-mode cranial point-of-care ultrasound (cPOCUS). Ultrasound has several advantages. It is a safe, non- invasive, low-cost, fast and portable bedside tool without ionizing radiation exposure.

Cranial Ultrasound for Point of Care Intracranial Pathology Detection in Pediatrics (CUPID-Peds)

Cranial Ultrasound for Point of Care Intracranial Pathology Detection in Pediatrics

Condition
Traumatic Brain Injury
Intervention / Treatment

-

Contacts and Locations

Charlotte

Atrium Health Carolinas Medical Center, Charlotte, North Carolina, United States, 28203

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Patients requiring a head computed tomography (CT) as the standard of care
  • * Seen in the pediatric Emergency Department or Pediatric Intensive Care Unit at Atrium Health Wake Forest Brenner Children's Hospital or Levine Children's Hospital
  • * Patients with open skull fractures
  • * Previous hemicraniectomy
  • * Existing surgical defect in the skull
  • * Patients being transitioned to comfort care

Ages Eligible for Study

to 18 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Wake Forest University Health Sciences,

Denise Fraga, MD, PRINCIPAL_INVESTIGATOR, Atrium Health Wake Forest Baptist

Study Record Dates

2026-04