Working Memory Training for People Aging with HIV

Description

The present study investigates the feasibility of working memory training in people aging with HIV (PAWHIV). In a cross-over design this stage 1 feasibility trial, will evaluate acceptability, and estimate possible effect sizes related to working memory training by examining potential differential effects in PAWHIV and those aging without HIV. This project highlights the importance of tailored cognitive assessments and interventions, engaging with underrepresented communities to enhance inclusivity in cognitive health research.

Conditions

Cognitive Change

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Study Overview

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Study Details

Study overview

The present study investigates the feasibility of working memory training in people aging with HIV (PAWHIV). In a cross-over design this stage 1 feasibility trial, will evaluate acceptability, and estimate possible effect sizes related to working memory training by examining potential differential effects in PAWHIV and those aging without HIV. This project highlights the importance of tailored cognitive assessments and interventions, engaging with underrepresented communities to enhance inclusivity in cognitive health research.

A Feasibility Study of Working Memory Training for People Aging with HIV

Working Memory Training for People Aging with HIV

Condition
Cognitive Change
Intervention / Treatment

-

Contacts and Locations

Boston

Northeastern University, Boston, Massachusetts, United States, 02115

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * 50-85 years of age
  • * Able to understand and speak English and follow study procedures
  • * Does not have a psychological or neurological condition that would prevent being able to give consent to participate
  • * Not currently involved in any other cognitive or memory training studies
  • * Formal diagnosis of dementia or other neurological disease, including Mild cognitive impairment.
  • * A final total score below 17 on Montreal Cognitive Assessment - Blind (telephone) version.
  • * Score of 10 or more on the Generalized Anxiety Questionnaire (GAD7; Spitzer et al., 2006, Archives of Internal Medicine), indicating presence of moderate or severe anxiety
  • * Score of 9 or more on Geriatric depression scale (GDS15; Yesavage et al., 1982) indicating presence of moderate or severe depression
  • * Abnormal visual acuity prohibitive of tablet-based training.
  • * Physical handicap (motor or perceptual) that would impede training procedures.
  • * Medical illness requiring treatment and/or significant absences during the study timeline.
  • * Current evidence or 2-yr history of seizures, focal brain lesion, or head injury with loss of consciousness.
  • * Current alcohol consumption exceeds 14 drinks per week.
  • * Self-reported illicit drug use.

Ages Eligible for Study

50 Years to 85 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

Northeastern University,

Susanne Jaeggi, PhD, PRINCIPAL_INVESTIGATOR, Northeastern University

Aaron Seitz, PRINCIPAL_INVESTIGATOR, Northeastern University

Study Record Dates

2025-12-31