RECRUITING

ReadMap: Reading in Stroke Alexia and Typical Aging

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Loss of reading ability due to stroke, called alexia, likely affects over a million Americans at any given time and causes difficulty performing many daily life functions, such as paying bills, using email/text, reading for pleasure, and reading signs in the community. Understanding the brain and cognitive basis of alexia could improve diagnosis and treatment of this important problem. In this study, the investigators will perform a large-scale behavioral and brain imaging study of stroke survivors and typical older adults to improve our understanding of the brain and cognitive basis of reading in both of these groups. Participants will complete a battery of tests of reading, speech, language, and thinking abilities. In addition, some participants will complete an MRI. Sessions will be completed across approximately 2-6 weeks, but may be extended depending on participants' schedules and availability. Some participants will be invited to repeat these procedures once or twice in approximately 3-12 months to monitor for changes in reading abilities and MRI measurements over time.

Official Title

ReadMap: Reading in Stroke Alexia and Typical Aging

Quick Facts

Study Start:2023-01-12
Study Completion:2028-08-31
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06700005

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Age \>= 18
  2. * Learned English at 8 years or younger
  3. * Brain injury resulting from stroke
  4. * Age \>= 18
  5. * Learned English at 8 years or younger
  6. * History of other brain disorder that could interfere with our ability to interpret results (e.g., Multiple sclerosis, dementia, head injury causing loss of consciousness)
  7. * Severe psychiatric condition that would interfere with participation in the study
  8. * History of diagnosed learning disorder
  9. * Hearing or vision loss that interferes with performance on behavioral tests even after correction with glasses/hearing aids.
  10. * Inability to follow study procedures despite maximal support
  11. * Presence of metal in the body that is incompatible with MRI
  12. * Pregnancy
  13. * Claustrophobia
  1. Pregnancy or breastfeeding
  2. Severe psychiatric disorders
  3. Active substance abuse
  4. Unstable medical conditions
  5. Inability to comply with study requirements

Contacts and Locations

Study Contact

Alycia Laks, MS, CCC-SLP
CONTACT
202-687-5205
crlab@georgetown.edu

Principal Investigator

Peter Turkeltaub, MD,PhD
PRINCIPAL_INVESTIGATOR
Georgetown University; MedStar National Rehabilitation Hospital

Study Locations (Sites)

Georgetown University Medical Center
Washington, District of Columbia, 20057
United States

Collaborators and Investigators

Sponsor: Georgetown University

  • Peter Turkeltaub, MD,PhD, PRINCIPAL_INVESTIGATOR, Georgetown University; MedStar National Rehabilitation Hospital

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2023-01-12
Study Completion Date2028-08-31

Study Record Updates

Study Start Date2023-01-12
Study Completion Date2028-08-31

Terms related to this study

Keywords Provided by Researchers

  • aphasia
  • stroke
  • brain injury
  • speech
  • language
  • reading
  • alexia
  • apraxia

Additional Relevant MeSH Terms

  • Aphasia
  • Stroke
  • Alexia