RECRUITING

Predicting Future Errors During Skill Performance

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Background: Many tasks people do every day require a series of individual movements. Control over these movements is called motor skills. But even highly skilled people can make mistakes. Researchers have found that they can predict when a person will make a mistake 0.1 second before it happens. Now, they want to find out if they can increase that time up to 1 second-long enough to warn the person and prevent the mistake. Objective: To see if motor skill errors can be detected up to 1 second before they occur. Eligibility: Right-handed healthy adults aged 18 to 35. Design: Participants will have 2 to 5 study visits. Each visit will be 1 to 2 hours. They will have a physical and neurological exam. They will have 1 or 2 magnetic resonance imaging (MRI) scans. They will lie on a table that slides into a large cylinder. The MRI uses strong magnets to capture images of the inside of the body, including the brain. They will have another scan, called magnetoencephalography (MEG). Small metal disks attached to wires will be taped to their head. Participants will sit in a padded chair with their head inside of a helmet. The helmet will not cover their eyes or face. Participants will perform a series of typing tasks on a keyboard. They will have short breaks between each round. Their head movements will be tracked, and their eye and finger movements will be videotaped.

Official Title

Predicting Future Errors During Skill Performance

Quick Facts

Study Start:2025-05-15
Study Completion:2029-10-01
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06707207

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 35 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT
Inclusion CriteriaExclusion Criteria
  1. * Stated willingness to comply with all study procedures and availability for the duration of the study
  2. * Male or female, aged 18-35
  3. * In good general health as evidenced by medical history and normal neurological examination as determined by the screening clinician
  4. * English speaking
  5. * Right-handedness as reported by participant.
  6. * Ability of subject to understand and the willingness to sign a written informed consent document.
  1. * HCPS-affiliated NIH staff (i.e. - staff from our section).
  2. * Current pregnancy.
  3. * Contraindications for MRI, or MEG
  4. * Severe or progressive neurological, psychological or medical condition as determined by the medical history review or physical and neurological exam.

Contacts and Locations

Study Contact

Catherine L Blumhorst, C.R.N.P.
CONTACT
(301) 451-1335
cathy.blumhorst@nih.gov
Leonardo G Cohen, M.D.
CONTACT
(301) 496-9782
cohenl1@mail.nih.gov

Principal Investigator

Leonardo G Cohen, M.D.
PRINCIPAL_INVESTIGATOR
National Institute of Neurological Disorders and Stroke (NINDS)

Study Locations (Sites)

National Institutes of Health Clinical Center
Bethesda, Maryland, 20892
United States

Collaborators and Investigators

Sponsor: National Institute of Neurological Disorders and Stroke (NINDS)

  • Leonardo G Cohen, M.D., PRINCIPAL_INVESTIGATOR, National Institute of Neurological Disorders and Stroke (NINDS)

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2025-05-15
Study Completion Date2029-10-01

Study Record Updates

Study Start Date2025-05-15
Study Completion Date2029-10-01

Terms related to this study

Keywords Provided by Researchers

  • Healthy
  • Brain
  • Motor Skill

Additional Relevant MeSH Terms

  • Healthy