COMPLETED

A Study to Learn About the Study Medicine Called PF-07976016 in Adults With Obesity

Conditions

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The purpose of this clinical trial is to learn about the safety and effects of the study medicine (called PF-07976016) for the potential treatment of obesity. The study will compare the experiences of participants taking the study medicine (PF-07976016) to those of participants who take placebo (a lookalike substance that contains no active study medicine). The aim is to measure the body's response to the study medicine, including any changes in participants' body weight and how well they tolerate the study medicine.

Official Title

A PHASE 2A, RANDOMIZED, DOUBLE-BLIND, SPONSOR-OPEN, PLACEBO-CONTROLLED, PARALLEL GROUP, DOSE-RANGING STUDY OF PF-07976016 TO ASSESS SAFETY AND EFFICACY IN ADULT PARTICIPANTS WITH OBESITY

Quick Facts

Study Start:2024-12-09
Study Completion:2026-01-12
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:COMPLETED

Study ID

NCT06717425

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 74 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Male or non-pregnant, non-breastfeeding female, 18 to 74 years of age at Visit 1
  2. * Body Mass Index ≥30.0 kg/m2 at Visit 1, with stable body weight, defined as \<5 kg change in the 12 weeks before Visit 1
  3. * Eligible and willing to receive required background medicine
  4. * Willing and able to comply with all study procedures
  1. * Any medical or psychiatric condition or laboratory abnormality, or recent serious illness or hospitalization, that may increase the risk of study participation or, in the investigator's judgment, make the participant inappropriate for the study including diagnosis of type 2 diabetes mellitus, type 1 or secondary forms of diabetes.
  2. * Use of any prohibited prior or concomitant medication(s)
  3. * Presence of specified abnormalities on diagnostic assessments including clinical laboratory tests at Visit 1.

Contacts and Locations

Principal Investigator

Pfizer CT.gov Call Center
STUDY_DIRECTOR
Pfizer

Study Locations (Sites)

Anaheim Clinical Trials, LLC
Anaheim, California, 92801
United States
Artemis Institute for Clinical Research
San Diego, California, 92103
United States
Clinical & Translational Research Center
Aurora, Colorado, 80045
United States
University of Colorado Anschutz Medical Campus
Aurora, Colorado, 80045
United States
Westside Center for Clinical Research
Jacksonville, Florida, 32205
United States
New Horizon Research Center
Miami, Florida, 33165
United States
Renstar Medical Research
Ocala, Florida, 34470
United States
Renstar Medical Research
Ocala, Florida, 34471
United States
St Johns Center for Clinical Research
Saint Augustine, Florida, 32086
United States
Rophe Adult and Pediatric Medicine/SKYCRNG
Union City, Georgia, 30291
United States
East-West Medical Research Institute
Honolulu, Hawaii, 96814
United States
Cotton O'Neil Diabetes & Endocrinology
Topeka, Kansas, 66606
United States
L-MARC Research Center
Louisville, Kentucky, 40213
United States
Pennington Biomedical Research Center
Baton Rouge, Louisiana, 70808
United States
StudyMetrix Research
City of Saint Peters, Missouri, 63303
United States
Rochester Clinical Research, LLC
Rochester, New York, 14609
United States
Accellacare - Wilmington
Wilmington, North Carolina, 28401
United States
AMR Clinical
Norman, Oklahoma, 73069
United States
Cornerstone Nutrition and Diabetes
Norman, Oklahoma, 73069
United States
Capital Area Research, LLC
Camp Hill, Pennsylvania, 17011
United States
Elligo Clinical Research Center
Austin, Texas, 78704
United States
Texas Diabetes & Endocrinology, P.A.
Austin, Texas, 78749
United States
Velocity Clinical Research, Dallas
Dallas, Texas, 75230
United States
UT Southwestern Medical Center
Dallas, Texas, 75390
United States
Consano Clinical Research, LLC
Shavano Park, Texas, 78231
United States
Chrysalis Clinical Research
St. George, Utah, 84790
United States
Southwest Internal Medicine, PC
St. George, Utah, 84790
United States
Selma Medical Associates
Winchester, Virginia, 22601
United States

Collaborators and Investigators

Sponsor: Pfizer

  • Pfizer CT.gov Call Center, STUDY_DIRECTOR, Pfizer

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2024-12-09
Study Completion Date2026-01-12

Study Record Updates

Study Start Date2024-12-09
Study Completion Date2026-01-12

Terms related to this study

Keywords Provided by Researchers

  • Obesity

Additional Relevant MeSH Terms

  • Obesity