Mindfulness and Placebo for Pain (MAPP) Study

Description

This study proposes a three-arm randomized-controlled trial (RCT) that evaluates the feasibility and acceptability of combining a mindfulness-based therapy (MBT) and open-label placebo (OLP) treatment for individuals with chronic pain. Individuals with chronic pain will be recruited to participate in an 8-week trial, with a subsequent 3-month post-treatment follow-up. Participants will be randomly assigned to one of the following three conditions: 1. Mindfulness-Based Stress Reduction (MBSR) 2. OLP treatment 3. combination of MBSR and OLP treatment

Conditions

Chronic Pain

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Study Overview

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Study Details

Study overview

This study proposes a three-arm randomized-controlled trial (RCT) that evaluates the feasibility and acceptability of combining a mindfulness-based therapy (MBT) and open-label placebo (OLP) treatment for individuals with chronic pain. Individuals with chronic pain will be recruited to participate in an 8-week trial, with a subsequent 3-month post-treatment follow-up. Participants will be randomly assigned to one of the following three conditions: 1. Mindfulness-Based Stress Reduction (MBSR) 2. OLP treatment 3. combination of MBSR and OLP treatment

Feasibility of Combining Mindfulness Intervention and Open-Label Placebo Treatment for Chronic Pain

Mindfulness and Placebo for Pain (MAPP) Study

Condition
Chronic Pain
Intervention / Treatment

-

Contacts and Locations

Phoenix

Arizona State University Downtown Phoenix Campus, Phoenix, Arizona, United States, 85004

Phoenix

Arizona State University, Phoenix, Arizona, United States, 85004

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • 1. ≥18 years old;
  • 2. ability to speak, write, and read in English;
  • 3. physical pain present on at least half the days in the past 3 months; and
  • 4. average past week pain severity rating ≥3 on a 0-10 Numerical Rating Scale.
  • 1. acute pain due to recent injury or surgery;
  • 2. self-reporting of chronic malignant pain (e.g., cancer, HIV);
  • 3. self-reporting of Raynaud's disease (those who can be contraindicated for cold pressor testing);
  • 4. severe psychopathology (e.g., a psychotic disorder) or significant cognitive deficits judged to interfere with study procedures;
  • 5. currently pregnant or breastfeeding;
  • 6. inability to discontinue use of vitamin B2 supplements or a multivitamin containing vitamin B2 throughout the study period (these interfere with riboflavin tracer-OLP treatment adherence-monitoring);
  • 7. inability to commit to study period.

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Arizona State University,

Chung Jung Mun, PhD, PRINCIPAL_INVESTIGATOR, Arizona State University

Study Record Dates

2027-03