A Study to Test Whether BI 771716 Helps People With an Advanced Form of Age-related Macular Degeneration (AMD) Called Geographic Atrophy

Description

This study is open to people 50 years or older with an eye condition called geographic atrophy. The purpose of this study is to compare a medicine called BI 771716 with a medicine called pegcetacoplan. BI 771716 is being developed to treat people with geographic atrophy. Pegcetacoplan is a medicine already used to treat people with geographic atrophy. In this study, participants receive either BI 771716 or pegcetacoplan as injections in the eye. Participants are in the study for a little longer than a year and visit the study site every 4 weeks. At the visits, the study doctor checks the eyes of the participants. The results are compared between the groups of participants to see whether the treatment works. The study doctor also regularly checks participants' health and takes note of any unwanted effects.

Conditions

Macular Degeneration, Age-related, Geographic Atrophy

Study Overview

Study Details

Study overview

This study is open to people 50 years or older with an eye condition called geographic atrophy. The purpose of this study is to compare a medicine called BI 771716 with a medicine called pegcetacoplan. BI 771716 is being developed to treat people with geographic atrophy. Pegcetacoplan is a medicine already used to treat people with geographic atrophy. In this study, participants receive either BI 771716 or pegcetacoplan as injections in the eye. Participants are in the study for a little longer than a year and visit the study site every 4 weeks. At the visits, the study doctor checks the eyes of the participants. The results are compared between the groups of participants to see whether the treatment works. The study doctor also regularly checks participants' health and takes note of any unwanted effects.

Randomized, Double-masked, actiVE-contRolleD, Multicenter Study to evaluAte Efficacy aNd safeTy of Two Regimens of Intravitreal BI 771716 Against Pegcetacoplan in Participants With Geographic Atrophy Secondary to Age-related Macular Degeneration VERDANT Trial

A Study to Test Whether BI 771716 Helps People With an Advanced Form of Age-related Macular Degeneration (AMD) Called Geographic Atrophy

Condition
Macular Degeneration, Age-related
Intervention / Treatment

-

Contacts and Locations

Gilbert

Associated Retina Consultants, Gilbert, Arizona, United States, 85297

Phoenix

Associated Retina Consultants, Ltd., Phoenix, Arizona, United States, 85020

Phoenix

Phoenix Retina Associates, Phoenix, Arizona, United States, 85050

Scottsdale

Retina Macula Institute of Arizona, Scottsdale, Arizona, United States, 85255

Sun City

Barnet Dulaney Perkins Eye Center, Sun City, Arizona, United States, 85351

Glendale

Global Research Management, Glendale, California, United States, 91204

Huntington Beach

Retina Associates of Southern California, Huntington Beach, California, United States, 92647

Modesto

Retinal Consultants Medical Group, Inc, Modesto, California, United States, 95356

Newport Beach

Eye Research Foundation, Newport Beach, California, United States, 92663

Poway

Retina Consultants of San Diego, Poway, California, United States, 92064

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

    Ages Eligible for Study

    50 Years to

    Sexes Eligible for Study

    ALL

    Accepts Healthy Volunteers

    No

    Collaborators and Investigators

    Boehringer Ingelheim,

    Study Record Dates

    2027-02-16