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Effect of Resveratrol Supplementation on Exercise Performance and Recovery

Conditions

Effect of Resveratrol on Performance and Recovery

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Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

To examine the effects of once daily supplementation with 500mg VeriSperse® resveratrol (VRES) for 17 days on muscle function, delayed onset muscle soreness, systemic concentrations of muscular damage markers and markers of oxidative stress in resistance trained young adult males following a damaging isoinertial squat protocol (ISP).

Official Title

The Effects of Resveratrol Supplementation on Functional and Systemic Markers of Muscle Damage and Cardiovascular Function in Response to a Damaging Isoinertial Squat Protocol

Quick Facts

Study Start:2024-10-01

Study Completion:2025-04-01

Study Type:Not specified

Phase:Not Applicable

Enrollment:Not specified

Status:RECRUITING

Study ID

NCT06723119

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 40 Years

Sexes Eligible for Study:MALE

Accepts Healthy Volunteers:Yes

Standard Ages:ADULT

Inclusion Criteria	Exclusion Criteria
* • Male between the ages of 18-40 years old * Healthy, and ready for physical activity as determined by the PAR-Q+, and MHQ. * Participants will be required to be recreationally active (defined according to ACSM standards of at least 150 minutes exercise per week). * Participants will be required to have been actively resistance training for a minimum of 6 months as defined by 3 resistance training sessions per week with at least one lower body session. * Participants must be willing to abstain from the consumption of bananas of non-steroidal anti-inflammatory drugs (NSAIDs) for the duration of their enrollment in study. * Participants must be willing to abstain from dietary supplementation that are viewed by study investigators to confound the outcomes of the study (e.g., Creatine). Those currently supplementing must be willing to undergo a 28-day washout prior to beginning study procedures. * Participants must be consuming \<300 mg·day-1 (Equivalent to 3 cups of coffee per day or 2 16oz cans of Redbull) and willing to keep their caffeine consumption consistent throughout the duration of the study. * Participants will be required to have access to the online MyFitnessPal application either via cellphone or computer and be willing to download and maintain the application for the duration of the study. * Free from previous or current lower body injuries that are viewed by the investigators to potentially limit ability of the participant to perform the assessments. * Willing to abstain from lower body resistance training for the 14 days preceding ET1 and ET2	* • Individual does not provide consent to participate in this study. * Inability to perform physical exercise (determined by MHQ, and PAR Q+). That is Answering "Yes" to any question on the PAR-Q +, or having a pre-existing condition such as musculoskeletal injury, back pain, chronic pain etc. that the investigative team perceives will prevent a participant from safely completing the protocol. * Not currently participating in at least 150 minutes of physical activity per week. * Not currently resistance trained (as defined within the inclusion criteria) * Currently taking any performance-enhancing drug (determined from health and activity questionnaire) * Currently taking a nutritional supplement known to improve physical performance and not willing refrain form the consumption of the supplement for at least 28-days prior to beginning study procedures. * Regularly taking any type of prescription or over-the-counter medication deemed to affect performance, or having any chronic illnesses, which require medical care. * Have used nicotine or tobacco at any time within the last three months. * Report consuming bananas or NSAIDS at any time during your enrollment in the study. * Report daily caffeine consumption \>300 mg·day-1 * Report any lower extremity muscle soreness for visits ET1 and ET2 * Previous or current lower body injuries viewed by the investigators to potentially limit the ability of the participant to perform the assessments. * Inability or unwillingness to consume the provided standardized snacks and meals in their entirety. * Inability or unwillingness to adhere to the diet restrictions of the study. * Have a food allergy to either of the two provided energy bars. * Inability or unwillingness to report all food and beverage consumption during the two 5-day dietary log periods.

Inclusion Criteria

Exclusion Criteria

* • Male between the ages of 18-40 years old
* Healthy, and ready for physical activity as determined by the PAR-Q+, and MHQ.
* Participants will be required to be recreationally active (defined according to ACSM standards of at least 150 minutes exercise per week).
* Participants will be required to have been actively resistance training for a minimum of 6 months as defined by 3 resistance training sessions per week with at least one lower body session.
* Participants must be willing to abstain from the consumption of bananas of non-steroidal anti-inflammatory drugs (NSAIDs) for the duration of their enrollment in study.
* Participants must be willing to abstain from dietary supplementation that are viewed by study investigators to confound the outcomes of the study (e.g., Creatine). Those currently supplementing must be willing to undergo a 28-day washout prior to beginning study procedures.
* Participants must be consuming \<300 mg·day-1 (Equivalent to 3 cups of coffee per day or 2 16oz cans of Redbull) and willing to keep their caffeine consumption consistent throughout the duration of the study.
* Participants will be required to have access to the online MyFitnessPal application either via cellphone or computer and be willing to download and maintain the application for the duration of the study.
* Free from previous or current lower body injuries that are viewed by the investigators to potentially limit ability of the participant to perform the assessments.
* Willing to abstain from lower body resistance training for the 14 days preceding ET1 and ET2

* • Individual does not provide consent to participate in this study.
* Inability to perform physical exercise (determined by MHQ, and PAR Q+). That is Answering "Yes" to any question on the PAR-Q +, or having a pre-existing condition such as musculoskeletal injury, back pain, chronic pain etc. that the investigative team perceives will prevent a participant from safely completing the protocol.
* Not currently participating in at least 150 minutes of physical activity per week.
* Not currently resistance trained (as defined within the inclusion criteria)
* Currently taking any performance-enhancing drug (determined from health and activity questionnaire)
* Currently taking a nutritional supplement known to improve physical performance and not willing refrain form the consumption of the supplement for at least 28-days prior to beginning study procedures.
* Regularly taking any type of prescription or over-the-counter medication deemed to affect performance, or having any chronic illnesses, which require medical care.
* Have used nicotine or tobacco at any time within the last three months.
* Report consuming bananas or NSAIDS at any time during your enrollment in the study.
* Report daily caffeine consumption \>300 mg·day-1
* Report any lower extremity muscle soreness for visits ET1 and ET2
* Previous or current lower body injuries viewed by the investigators to potentially limit the ability of the participant to perform the assessments.
* Inability or unwillingness to consume the provided standardized snacks and meals in their entirety.
* Inability or unwillingness to adhere to the diet restrictions of the study.
* Have a food allergy to either of the two provided energy bars.
* Inability or unwillingness to report all food and beverage consumption during the two 5-day dietary log periods.

Contacts and Locations

Study Contact

Trevor Dufner

CONTACT

701-205-8690

trevor.dufner@ucf.edu

Study Locations (Sites)

University of Central Florida EPIC Lab

Orlando, Florida, 32816

United States

Collaborators and Investigators

Sponsor: University of Central Florida

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2024-10-01

Study Completion Date2025-04-01

Study Record Updates

Study Start Date2024-10-01

Study Completion Date2025-04-01

Terms related to this study

Additional Relevant MeSH Terms

Effect of Resveratrol on Performance and Recovery