Post-Stroke Sensory Reweighting on Walking and Balance Outcomes

Description

The primary objective of this proof-of-concept study is to longitudinally track the development of post-stroke sensory reweighting (PSR), identify associated structural neuroanatomical correlates, and investigate their relationship to walking and fall outcomes.

Conditions

Ischemic Stroke

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Study Overview

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Study Details

Study overview

The primary objective of this proof-of-concept study is to longitudinally track the development of post-stroke sensory reweighting (PSR), identify associated structural neuroanatomical correlates, and investigate their relationship to walking and fall outcomes.

Tracking the Development and Influence of Post-Stroke Sensory Reweighting on Walking and Balance Outcomes

Post-Stroke Sensory Reweighting on Walking and Balance Outcomes

Condition
Ischemic Stroke
Intervention / Treatment

-

Contacts and Locations

Cincinnati

University of Cincinnati College of Medicine, Cincinnati, Ohio, United States, 45267

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • 1. First ever clinical stroke
  • 2. Stroke due to ischemia
  • 3. Age 18 years or older
  • 4. Ability to consent by patient (not surrogate), any time prior to acute hospital discharge
  • 1. Pre-stroke dependence (modified Rankin Scale score of 3 or more)
  • 2. Isolated brainstem or cerebellar stroke
  • 3. Bilateral acute strokes
  • 4. Co-enrollment in a trial of an intervention through six-month follow-up
  • 5. Inability to maintain follow-up with study procedures through six-month follow-up
  • 6. Contraindication to non-contrast MRI
  • 7. Low likelihood of survival beyond the acute hospitalization, such as malignant cerebral edema
  • 8. Pre-existing co-morbid conditions that significantly affects vision, somatosensory function, vestibular system, orthostasis, coordination or mobility
  • 9. Post stroke mRS\>4 or discharge to hospice

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

University of Cincinnati,

Oluwole Awosika, MD, MSCR, PRINCIPAL_INVESTIGATOR, University of

Study Record Dates

2026-08-30