Exploring Neurophysiological Markers of Brain Health

Description

The combination of transcranial magnetic stimulation (TMS) and electroencephalography (EEG) has been suggested as a promising brain imaging tool for identifying biomarkers of brain health. In this pilot study, study investigators will explore the neurophysiological metrics of brain health with a non-invasive brain imaging technique, alongside behavioral and fMRI metrics collected through another study (NCT04869111).

Conditions

Healthy Lifestyle, Health-Related Behavior

Study Overview

Study Details

Study overview

The combination of transcranial magnetic stimulation (TMS) and electroencephalography (EEG) has been suggested as a promising brain imaging tool for identifying biomarkers of brain health. In this pilot study, study investigators will explore the neurophysiological metrics of brain health with a non-invasive brain imaging technique, alongside behavioral and fMRI metrics collected through another study (NCT04869111).

Exploring Markers of Brain Health With EEG and TMS: A Pilot Study

Exploring Neurophysiological Markers of Brain Health

Condition
Healthy Lifestyle
Intervention / Treatment

-

Contacts and Locations

Dallas

Center for BrainHealth at The University of Texas at Dallas, Dallas, Texas, United States, 75235

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Must be an active brain imaging participant in The BrainHealth Project (NCT04869111)
  • * Minimum age of 22
  • * Fluent in English
  • * Able to read \& hear information over a computer
  • * Must pass an MRI safety screener to assess the presence of contraindicators for MRI compatibility (i.e., non-removable metal within/on the body, claustrophobia, pregnancy, non-correctable vision problems, head trauma, and CNS disease)or other standard requirements as determined by the Imaging Center.
  • * Must pass a modified TMS Adult Safety Screen
  • * Meet all criteria for study as determined by the study physician
  • * A diagnosis of a neurodegenerative disease
  • * A history of stroke, concussion, or brain injury that currently hinders them from functioning at their prior level
  • * A diagnosis of autism spectrum disorder that currently hinders them from functioning independently.
  • * Metallic brain implants or fragments (like a shunt, pacemaker, clips, coils, bullet fragments, cochlear implants)
  • * Magnetically activated implants or electronically implanted devices
  • * Medication pumps
  • * Personal or family history of epilepsy, seizure(s), seizure disorder.
  • * History of, or risk factors for syncope (fainting)
  • * Report significant cognitive challenges
  • * Report untreated health issues (like substance abuse, hypertension, hypo- or hyper-thyroidism)
  • * Have claustrophobia

Ages Eligible for Study

22 Years to 100 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

The University of Texas at Dallas,

Sandra Chapman, PhD, PRINCIPAL_INVESTIGATOR, University of Texas at Dallas

Study Record Dates

2027-05-31