Working Memory Training in Patients with Mild Cognitive Impairment

Description

The purpose of this study is to test whether a special memory training program, called CogMed, can help people with early memory problems. The Investigators want to see if this training improves memory and also helps reduce stress. The Investigators also want to see if CogMed results in changes to a blood biomarker called p-Tau 217, which possibly indicate Alzheimer's disease (AD).

Conditions

Mild Cognitive Impairment (MCI)

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Study Overview

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Study Details

Study overview

The purpose of this study is to test whether a special memory training program, called CogMed, can help people with early memory problems. The Investigators want to see if this training improves memory and also helps reduce stress. The Investigators also want to see if CogMed results in changes to a blood biomarker called p-Tau 217, which possibly indicate Alzheimer's disease (AD).

CogMed Intervention Targeting Working Memory in Patients with Mild Cognitive Impairment

Working Memory Training in Patients with Mild Cognitive Impairment

Condition
Mild Cognitive Impairment (MCI)
Intervention / Treatment

-

Contacts and Locations

Phoenix

Barrow Neurological Institute, Division of Alzheimer's Disease, Phoenix, Arizona, United States, 85013

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • 1. Male or female outpatients ages ≥ 50 years;
  • 2. Meet Mayo Clinic Criteria for MCI. (Patients with mild cognitive impairment)
  • 3. Access to the internet through computer
  • 4. A proficiency in speaking and reading English or having a family member who is proficient in reading and speaking English and is willing to serve as a translator.
  • 5. Vision and hearing must be sufficient to comply with study procedures.
  • 1. Mini Mental State Exam (MMSE) score less than 19 or patients diagnosed with moderate or severe dementia by a clinician.
  • 2. In the opinion of the investigator, participation would not be in the best interest of the subject.

Ages Eligible for Study

50 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

St. Joseph's Hospital and Medical Center, Phoenix,

Yonas E Geda, M.D, MSc, PRINCIPAL_INVESTIGATOR, Barrow Neurological Institute, Alzheimer's Disease and Cognitive Disorders Division

Study Record Dates

2025-09-30