RECRUITING

Ketogenic Diets for Weight Loss Maintenance: Impact on Energy Expenditure and Appetite in Individuals With Obesity

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Conditions

ObesityKetogenic DietWeight lossWeight loss maintenanceAppetiteEnergy expenditure

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Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The goal of this clinical trial is to investigate whether a Ketogenic Diet (KD) can increase Total Energy Expenditure (TEE), while benefiting appetite, during weight loss maintenance in reduced-obese individuals.

Official Title

Ketogenic Diets for Weight Loss Maintenance: Impact on Energy Expenditure and Appetite in Individuals With Obesity

Quick Facts

Study Start:2025-08-01
Study Completion:2026-03-31
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06736028

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 65 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * BMI 30-45 kg/m2
  2. * Both men and women
  3. * Age between 18-65 years
  4. * Sedentary to moderately active (\<2 h/wk of moderate, structured, intentional, exercise)
  1. * Pregnancy or lactation
  2. * Daily use of tobacco (\>1 pk/wk)
  3. * Change in weight greater than 5 lb in the previous 3 months
  4. * Cognitive impairment
  5. * Previous bariatric surgery
  6. * History of eating disorder
  7. * Presence of any condition (e.g. DM2, PCOS, inflammatory disease, untreated thyroid disease, fluid overload states such as chronic kidney disease, congestive heart failure, or cirrhosis)
  8. * Use of any medication (e.g., glucocorticoid, GLP-1 analogues, hormone replacement therapy) deemed to interfere with study outcomes.
  9. * Pre-menopausal women will need to have a regular menstrual cycle (28+/-2 days) or be on hormonal contraceptives
  10. * Fasting glucose plasma concentration \>125 mg/dl and/or HbA1c \> 6.4%

Contacts and Locations

Study Contact

Catia Martins, PhD
CONTACT
205-934-7922
catia197@uab.edu

Study Locations (Sites)

University of Alabama at Birmingham
Birmingham, Alabama, 35294
United States

Collaborators and Investigators

Sponsor: University of Alabama at Birmingham

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2025-08-01
Study Completion Date2026-03-31

Study Record Updates

Study Start Date2025-08-01
Study Completion Date2026-03-31

Terms related to this study

Keywords Provided by Researchers

  • Ketogenic Diet
  • Weight loss
  • Weight loss maintenance
  • Appetite
  • Energy expenditure

Additional Relevant MeSH Terms

  • Obesity