RECRUITING

Progressive Achilles Loading Via Clinician E-support

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

This is a randomized controlled trial with individuals who have Achilles tendon pain. This study is designed to identify an effective rehabilitation program for Achilles tendon pain that expands access to care for military personnel and to predict treatment response. Limited or delayed access to healthcare can exacerbate the severity of pain and duration of disability due to AT. This is particularly relevant for individuals deployed to battlefield settings or are being seen in busy military treatment facilities. Therefore, it is crucial to identify efficient and effective treatment pathways that maximize healthcare access and facilitate a rapid and pain-free return to full duty.

Official Title

Progressive Achilles Loading Via Clinician E-support (PACE)

Quick Facts

Study Start:2025-08-20
Study Completion:2028-07
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06736795

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 60 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT
Inclusion CriteriaExclusion Criteria
  1. * Pain localized to the Achilles tendon (insertion or midportion)
  2. * AT pain greater than or equal to 3/10 with tendon-loading exercise
  1. * Younger than 18 years of age or older than 60 years of age
  2. * BMI \> 45 kg/m2
  3. * Pain primarily due to a differential diagnosis, including paratendonitis, bursitis (retrocalcaneal or subcutaneous), posterior ankle impingement or os trigonum, irritation or neuropathy of the sural nerve, plantaris tendon involvement)
  4. * Presence of a partial Achilles tendon tear or rupture on imaging or a history of Achilles tendon rupture that was verified by surgical or conservative management
  5. * Attended physical therapy for AT in the past 3 months
  6. * History of steroid injection to lower extremity tendons/fascia, ESWT or any injection to the Achilles tendon region in the past 3 months
  7. * History of taking fluoroquinolones in the past 6 months
  8. * History of surgery or invasive procedure for AT on side enrolling for treatment
  9. * Diagnosed systemic inflammatory conditions (e.g., rheumatoid arthritis, ankylosing spondylitis), endocrine disorder with complications (e.g., uncontrolled Type I or II diabetes, diabetic peripheral neuropathy), connective tissue disorder (e.g., Marfan's syndrome, Ehlers Danlos), or pregnancy
  10. * At high risk for falls (four step square test \>15 seconds)
  11. * Refusal of randomization or unable or uninterested in completing virtual visits with a webcam or smart phone or completing quizzes and surveys

Contacts and Locations

Study Contact

Jessica Danielson, DDS
CONTACT
319-356-1722
chimenti-lab@uiowa.edu
Jessica F Danielson, DDS
CONTACT
319-356-1722
Jessica-danielson@uiowa.edu

Principal Investigator

Ruth L Chimenti, PT, PhD
PRINCIPAL_INVESTIGATOR
University of Iowa
Matthew Frazier, PT, DPT, MS, ATC
STUDY_DIRECTOR
Carl R. Darnall Army Medical Center (CRDAMC), Fort Cavazos

Study Locations (Sites)

University of Iowa Health Care - Gait Analysis Laboratory
Iowa City, Iowa, 52242
United States
Carl R. Darnall Army Medical Center (CRDAMC)
Fort Cavazos, Texas, 76544
United States

Collaborators and Investigators

Sponsor: Ruth Chimenti

  • Ruth L Chimenti, PT, PhD, PRINCIPAL_INVESTIGATOR, University of Iowa
  • Matthew Frazier, PT, DPT, MS, ATC, STUDY_DIRECTOR, Carl R. Darnall Army Medical Center (CRDAMC), Fort Cavazos

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2025-08-20
Study Completion Date2028-07

Study Record Updates

Study Start Date2025-08-20
Study Completion Date2028-07

Terms related to this study

Keywords Provided by Researchers

  • ultrasound imaging
  • tendon health
  • pain
  • exercise
  • physical therapy
  • education

Additional Relevant MeSH Terms

  • Achilles Tendon Pain
  • Achilles Tendinopathy