12-hour Time Limited Feeding in Critical Care

Description

This study is being done to assess the feasibility and safety of a time-restricted 12-hour enteral feeding protocol (experimental group) in comparison to a standard-of-care, 24-hour enteral feeding protocol (control group) in critically ill patients. Investigators hope to gain knowledge about how these feeding schedules affect feeding tolerance, blood sugar control, and other factors affecting critically ill adult patients. * Investigators expect that the 12-hour feeding protocol will be tolerated similarly to the 24-hour feeding protocol and will not result in a greater number of adverse events related to feeding. * Investigators expect that the proportion of participants in both groups receiving at least 75% of their estimated nutrition needs will be similar.

Conditions

Critical Illness

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Study Overview

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Study Details

Study overview

This study is being done to assess the feasibility and safety of a time-restricted 12-hour enteral feeding protocol (experimental group) in comparison to a standard-of-care, 24-hour enteral feeding protocol (control group) in critically ill patients. Investigators hope to gain knowledge about how these feeding schedules affect feeding tolerance, blood sugar control, and other factors affecting critically ill adult patients. * Investigators expect that the 12-hour feeding protocol will be tolerated similarly to the 24-hour feeding protocol and will not result in a greater number of adverse events related to feeding. * Investigators expect that the proportion of participants in both groups receiving at least 75% of their estimated nutrition needs will be similar.

The Safety and Feasibility of a 12-hour Time-Limited Enteral Feeding Protocol in Critically Ill Adults

12-hour Time Limited Feeding in Critical Care

Condition
Critical Illness
Intervention / Treatment

-

Contacts and Locations

Kansas City

University Of Kansas Health System, Kansas City, Kansas, United States, 66103

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Adults (≥18 years of age)
  • * With critical illness (hospitalized in an intensive care unit with a status of "ICU")
  • * Who have received orders for continuous enteral nutrition
  • * "Comfort Measures Only" status
  • * Have orders to receive trickle feedings (feeding rate ≤10mL/hr)
  • * Recent surgical procedure on the GI tract (within previous 5 days at time of recruitment) or admission for GI bleed
  • * Receiving continuous sedation
  • * Expected to undergo a procedure requiring removal of study devices in the three days following enrollment
  • * History of malabsorptive bariatric surgery
  • * Admitted for a burn injury
  • * Known intolerance to feeding rates \>100mL/hr
  • * Current diagnosis of pancreatitis, ileus or gastroparesis (only if using a gastrostomy tube)
  • * Requiring intermittent or continuous renal replacement therapy
  • * Pregnant or lactating
  • * On an intermittent feeding schedule
  • * Nutritional needs would require a rate higher than 120mL/hr on TRF12 protocol
  • * Lack of clearance by primary physician

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

University of Kansas Medical Center,

Felicia Steger, PhD, MS, RD, PRINCIPAL_INVESTIGATOR, University of Kansas Medical Center

Study Record Dates

2025-12