RECRUITING

The INSPIRE Study: Intervention Strategies for Preserving Intellectual Resilience and Engagement

Description

The INSPIRE Study, initiated by the Healthy Minds Initiative, is a community-based research project aimed at demonstrating the impact of lifestyle factors on cognitive health and the prevention of dementia. Conducted in collaboration with the American College of Lifestyle Medicine, Charles Drew University, UCLA, Stanford University and Crenshaw Christian Center, this study focuses on African American communities that are disproportionately affected by lifestyle-dependent diseases. The study involves 2,000 participants aged 55 and older and aims to directly address these disparities by implementing targeted interventions to enhance cognitive function and overall brain health.

Conditions

Dementia
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Related Conditions:

Dementia

Study Overview

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Study Details

Study overview

The INSPIRE Study, initiated by the Healthy Minds Initiative, is a community-based research project aimed at demonstrating the impact of lifestyle factors on cognitive health and the prevention of dementia. Conducted in collaboration with the American College of Lifestyle Medicine, Charles Drew University, UCLA, Stanford University and Crenshaw Christian Center, this study focuses on African American communities that are disproportionately affected by lifestyle-dependent diseases. The study involves 2,000 participants aged 55 and older and aims to directly address these disparities by implementing targeted interventions to enhance cognitive function and overall brain health.

Intervention Strategies for Preserving Intellectual Resilience and Engagement

The INSPIRE Study: Intervention Strategies for Preserving Intellectual Resilience and Engagement

Condition
Dementia
Intervention / Treatment

-

Contacts and Locations

Los Angeles

Crenshaw Christian Center, Los Angeles, California, United States, 90044

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Age: Participants must be 55 years of age or older.
  • * Ethnicity: Focused on African American individuals, but not exclusive.
  • * Cognitive Status: Participants must have normal cognitive status, mild cognitive impairment (MCI), or subjective cognitive impairment (SCI).
  • * Language: Participants must be fluent in English.
  • * Location: Must reside in the Crenshaw, California area or be able to attend study-related activities in this location.
  • * Willingness to Participate: Participants must be willing to adhere to the study protocol, including attending assessments, participating in interventions, and completing questionnaires.
  • * Cognitive Decline: Diagnosis of dementia or severe cognitive impairment that would interfere with the ability to participate in the study.
  • * Physical Limitations: Any physical or medical condition that would preclude participation in the lifestyle interventions (e.g., severe mobility issues).
  • * Recent Cancer Diagnosis: Diagnosis of cancer within the last three years, excluding stable cases of basal cell or squamous cell carcinoma of the skin, or stable prostate cancer.
  • * Pregnancy: Current pregnancy or planning to become pregnant during the study period.
  • * Mental Health: Diagnosis of severe psychiatric disorders such as schizophrenia or bipolar disorder that might interfere with participation.
  • * Substance Abuse: Current substance abuse or dependency that could impact participation.
  • * Hearing Impairment: Uncorrected hearing loss that would limit the ability to communicate and participate in the study.
  • * Non-English Speaking: Inability to participate in English-language oral and written cognitive assessments.
  • * Participation in Another Study: Currently enrolled in another clinical trial that could interfere with the INSPIRE Study.
  • * Life expectancy less than 3 years
  • * Unwillingness to share medical and laboratory information.

Ages Eligible for Study

55 Years to 85 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

Healthy Minds Initiative,

Dean Sherzai, MD, PhD, PRINCIPAL_INVESTIGATOR, Healthy Minds Initiative

Study Record Dates

2027-12-01