RECRUITING

IMAGINE: Pilot Trial of a Digital Group Intervention to Prevent Perinatal Depression

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The goal of this clinical trial is to evaluate if a digital group intervention (named IMAGINE) can prevent depression in perinatal populations. The main questions it aims to answer are: Does IMAGINE engage cognitive behavioral therapy targets? Does IMAGINE lead to lower depression scores? Is IMAGINE acceptable, appropriate, usable and feasible? Participants will be randomized to either participate in an IMAGINE group for 12 weeks or receive standard of care. Participants will respond to questionnaires at enrollment and study visits at 12 and 24 weeks after enrollment.

Official Title

IMAGINE: Pilot Trial of a Digital Group Intervention to Prevent Perinatal Depression

Quick Facts

Study Start:2025-03-10
Study Completion:2026-02-28
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06746337

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:16 Years
Sexes Eligible for Study:FEMALE
Accepts Healthy Volunteers:Yes
Standard Ages:CHILD, ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Pregnant or up to 6 months postpartum
  2. * Age 16 or over
  3. * At elevated risk of perinatal depression (per USPSTF)
  4. * Speaks English or Spanish
  5. * PHQ9\<15 and no current major depression
  6. * Access to a smartphone with cellular data at least 3 days per week
  7. * If receiving other mental healthcare services, has been established in care at least 6 months and on stable treatment regimen
  1. Pregnancy or breastfeeding
  2. Severe psychiatric disorders
  3. Active substance abuse
  4. Unstable medical conditions
  5. Inability to comply with study requirements

Contacts and Locations

Study Contact

Keshet Ronen, PhD, MPH
CONTACT
206-685-4363
keshet@uw.edu
Jaclyn Escudero, MPH
CONTACT
jne23@uw.edu

Principal Investigator

Keshet Ronen, PhD, MPH
PRINCIPAL_INVESTIGATOR
University of Washington

Study Locations (Sites)

Perinatal Support Washington
Seattle, Washington, 98103
United States

Collaborators and Investigators

Sponsor: University of Washington

  • Keshet Ronen, PhD, MPH, PRINCIPAL_INVESTIGATOR, University of Washington

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2025-03-10
Study Completion Date2026-02-28

Study Record Updates

Study Start Date2025-03-10
Study Completion Date2026-02-28

Terms related to this study

Keywords Provided by Researchers

  • digital
  • perinatal
  • depression

Additional Relevant MeSH Terms

  • Depression During Pregnancy
  • Depression, Postpartum