IMAGINE: Pilot Trial of a Digital Group Intervention to Prevent Perinatal Depression

Description

The goal of this clinical trial is to evaluate if a digital group intervention (named IMAGINE) can prevent depression in perinatal populations. The main questions it aims to answer are: Does IMAGINE engage cognitive behavioral therapy targets? Does IMAGINE lead to lower depression scores? Is IMAGINE acceptable, appropriate, usable and feasible? Participants will be randomized to either participate in an IMAGINE group for 12 weeks or receive standard of care. Participants will respond to questionnaires at enrollment and study visits at 12 and 24 weeks after enrollment.

Conditions

Depression During Pregnancy, Depression, Postpartum

Study Overview

Study Details

Study overview

The goal of this clinical trial is to evaluate if a digital group intervention (named IMAGINE) can prevent depression in perinatal populations. The main questions it aims to answer are: Does IMAGINE engage cognitive behavioral therapy targets? Does IMAGINE lead to lower depression scores? Is IMAGINE acceptable, appropriate, usable and feasible? Participants will be randomized to either participate in an IMAGINE group for 12 weeks or receive standard of care. Participants will respond to questionnaires at enrollment and study visits at 12 and 24 weeks after enrollment.

IMAGINE: Pilot Trial of a Digital Group Intervention to Prevent Perinatal Depression

IMAGINE: Pilot Trial of a Digital Group Intervention to Prevent Perinatal Depression

Condition
Depression During Pregnancy
Intervention / Treatment

-

Contacts and Locations

Seattle

Perinatal Support Washington, Seattle, Washington, United States, 98103

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Pregnant or up to 6 months postpartum
  • * Age 16 or over
  • * At elevated risk of perinatal depression (per USPSTF)
  • * Speaks English or Spanish
  • * PHQ9\<15 and no current major depression
  • * Access to a smartphone with cellular data at least 3 days per week
  • * If receiving other mental healthcare services, has been established in care at least 6 months and on stable treatment regimen

Ages Eligible for Study

16 Years to

Sexes Eligible for Study

FEMALE

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

University of Washington,

Keshet Ronen, PhD, MPH, PRINCIPAL_INVESTIGATOR, University of Washington

Study Record Dates

2026-02-28