Lipoprotein Interactions and Platelet Function in Healthy Individuals and Those with Lipid Disorders

Description

This study looks at how lipoproteins, which are particles in the blood that transport cholesterol, influence heart and blood vessel health. Beyond just their levels, the way these particles function plays a key role in preventing or contributing to disease. In some conditions, like high cholesterol or diabetes, lipoproteins may not work properly, increasing the risk of clogged arteries and other complications. The investigators aim to study these changes in people with lipid disorders to better understand their impact on blood health and to find new ways to prevent and treat heart disease.

Conditions

Lipid Disorders

Study Overview

Study Details

Study overview

This study looks at how lipoproteins, which are particles in the blood that transport cholesterol, influence heart and blood vessel health. Beyond just their levels, the way these particles function plays a key role in preventing or contributing to disease. In some conditions, like high cholesterol or diabetes, lipoproteins may not work properly, increasing the risk of clogged arteries and other complications. The investigators aim to study these changes in people with lipid disorders to better understand their impact on blood health and to find new ways to prevent and treat heart disease.

Lipoprotein Functions in Healthy Individuals and Subjects with Lipid Disorders

Lipoprotein Interactions and Platelet Function in Healthy Individuals and Those with Lipid Disorders

Condition
Lipid Disorders
Intervention / Treatment

-

Contacts and Locations

East Providence

Brown University Health Lipid Clinic, East Providence, Rhode Island, United States, 02914

Providence

Cardiovascular Research Center, Providence, Rhode Island, United States, 02903

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Healthy volunteers
  • * Abnormalities in lipid panels
  • * Able to provide informed consent
  • * Between the age of 18 and 69
  • * Drug or alcohol abuse within 6 months or significant mental/psychological impairment
  • * Current smokers
  • * Subjects with known bleeding disorders (for example, hemophilia)
  • * Subjects requiring regular transfusions for any reason
  • * No ethnic/racial groups will be excluded

Ages Eligible for Study

18 Years to 69 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

The Miriam Hospital,

Study Record Dates

2029-07-18