RECRUITING

Polycystic Kidney Disease 1 (PKD1) Gene Variant Groups in Autosomal Dominant Polycystic Kidney Disease

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Conditions

Autosomal Dominant Polycystic Kidney Disease (ADPKD)

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Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The purpose of this study is to estimate the prevalence, demographic, and clinical characteristics of PKD1/2 gene variant groups in the ADPKD population.

Official Title

A Study to Determine the Prevalence and Clinical Characteristics Associated With PKD1 Gene Variant Groups in Autosomal Dominant Polycystic Kidney Disease (ADPKD)

Quick Facts

Study Start:2025-01
Study Completion:2026-12
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06747572

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:12 Years to 65 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:CHILD, ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Estimated glomerular filtration rate (eGFR) greater than or equal to (≥) 30 milliliter per minute (mL/min)/1.73 m\^2
  2. * Willing and able to comply with scheduled visits and other study procedures
  3. * A pre-existing diagnosis of ADPKD as defined in the protocol
  1. * History of kidney disease other than ADPKD that in the opinion of the investigator would independently impact the natural history of ADPKD
  2. * History of solid organ or bone marrow transplantation or nephrectomy
  3. * Ongoing renal replacement therapy or planning to start renal replacement therapy less than or equal to (≤)12 months from the Genotyping Visit in Part A

Contacts and Locations

Study Contact

Medical Information
CONTACT
617-341-6777
medicalinfo@vrtx.com

Study Locations (Sites)

Alabama Kidney Research
Alabaster, Alabama, 35007
United States
Nature Coast Clinical Research - Inverness
Inverness, Florida, 34452
United States
Renal Associates, LLC
Columbus, Georgia, 31904
United States
Quest Research Institute
Farmington Hills, Michigan, 48334
United States
DaVita Clinical Research
Las Vegas, Nevada, 89107
United States

Collaborators and Investigators

Sponsor: Vertex Pharmaceuticals Incorporated

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2025-01
Study Completion Date2026-12

Study Record Updates

Study Start Date2025-01
Study Completion Date2026-12

Terms related to this study

Additional Relevant MeSH Terms

  • Autosomal Dominant Polycystic Kidney Disease (ADPKD)