The Impact of Melatonin Lotion on Sleep and Mental Health

Description

The purpose of this study is to examine the effect that melatonin lotion has on sleep quality, the nervous system, and mental health. Melatonin is a hormone secreted by the brain that regulates sleep and might improve depression and anxiety symptoms. The goal is to determine whether melatonin in lotion form is an effective treatment for young adults with inadequate sleep and might improve mental health. Participants will fill out surveys, wear an actigraph (a wrist-worn device that measures sleep), wear a heart rate monitor (a strap worn around one's chest), and provide nightly saliva samples during treatment weeks. In one of the two treatment weeks, participants will receive a lotion that contains melatonin. During the other week they will receive a control treatment that will be lotion with no melatonin, and there will be a week in between with no treatment at all.

Conditions

Sleep Problems, Depressive Disorder and Anxiety Disorders

Study Overview

Study Details

Study overview

The purpose of this study is to examine the effect that melatonin lotion has on sleep quality, the nervous system, and mental health. Melatonin is a hormone secreted by the brain that regulates sleep and might improve depression and anxiety symptoms. The goal is to determine whether melatonin in lotion form is an effective treatment for young adults with inadequate sleep and might improve mental health. Participants will fill out surveys, wear an actigraph (a wrist-worn device that measures sleep), wear a heart rate monitor (a strap worn around one's chest), and provide nightly saliva samples during treatment weeks. In one of the two treatment weeks, participants will receive a lotion that contains melatonin. During the other week they will receive a control treatment that will be lotion with no melatonin, and there will be a week in between with no treatment at all.

The Impact of Melatonin Lotion on Actigraphy, Sleep Quality, Autonomic Nervous System Indicators, Mood, Anxiety Symptoms, and Side Effects

The Impact of Melatonin Lotion on Sleep and Mental Health

Condition
Sleep Problems
Intervention / Treatment

-

Contacts and Locations

Redlands

University of Redlands, Redlands, California, United States, 92374

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * a T score ≥ 48 on the sleep disturbance short form Patient-Reported Outcomes Measurement Information System (PROMIS) measure, and
  • * a T score ≥ 55 on the anxiety or depression short form PROMIS measures (mild symptoms or more)
  • * currently using antidepressant, anti-anxiety, or sleep medication including melatonin
  • * are pregnant
  • * have allergies/sensitivities to scented lotion
  • * are unwilling to commit to keeping a similar bedtime (± 1 hour) during treatment weeks.

Ages Eligible for Study

18 Years to 21 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

University of Redlands,

Lisa E Olson, Ph.D., PRINCIPAL_INVESTIGATOR, University of Redlands

Study Record Dates

2028-04-01