RECRUITING

Optimizing a Remote-based Physical Activity Intervention for Adults with Total Knee Replacement

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The purpose of this study is to identify which supplemental intervention components added to an online exercise program contribute to the greatest increases in physical activity (total MVPA and percent meeting guidelines \[≥150 min/week of MVPA\]) in adults with knee replacement at 6 and 12 months. Secondary outcomes will examine changes in pain and physical function.

Official Title

Optimizing a Remote-based Physical Activity Intervention for Adults with Total Knee Replacement

Quick Facts

Study Start:2025-01-21
Study Completion:2029-07-31
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06768762

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * had a knee replacement (including primary, staged or independent bilateral, or revision) at least 12 months ago
  2. * have a computer, tablet, or smartphone with active internet access
  3. * self-report engaging in less than 60 minutes/week of moderate-intensity physical activity
  4. * be English-speaking and able to read consent and study materials written in English
  5. * be willing to complete the 4 remote assessments, including physical activity monitoring
  6. * be willing to be randomized to receive 0-4 supplemental intervention components.
  1. * any contraindications to physical activity (e.g., chest pain)
  2. * have a scheduled surgery within the next 12 months (e.g., hip or knee replacement)
  3. * have a mobility limiting comorbidity unrelated to knee replacement
  4. * live outside of the continental U.S
  5. * do not currently have a physician or orthopedic surgeon whom they see regularly
  6. * are currently participating in physical therapy (for knee)
  7. * are participating in a structured weight loss or physical activity program
  8. * unable to provide proof of knee replacement surgery
  9. * have a BMI \>40kg/m2
  10. * score \>30 on PROMIS cognitive function

Contacts and Locations

Study Contact

Jakob Nelson, MS
CONTACT
803-766-6960
JAKOBRN@email.sc.edu
Christine Pellegrini, PhD
CONTACT
803-777-0911
pellegca@mailbox.sc.edu

Principal Investigator

Christine Pellegrini, PhD
PRINCIPAL_INVESTIGATOR
University of South Carolina
Jessica Unick, PhD
PRINCIPAL_INVESTIGATOR
The Miriam Hospital

Study Locations (Sites)

University of South Carolina
Columbia, South Carolina, 29208
United States

Collaborators and Investigators

Sponsor: University of South Carolina

  • Christine Pellegrini, PhD, PRINCIPAL_INVESTIGATOR, University of South Carolina
  • Jessica Unick, PhD, PRINCIPAL_INVESTIGATOR, The Miriam Hospital

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2025-01-21
Study Completion Date2029-07-31

Study Record Updates

Study Start Date2025-01-21
Study Completion Date2029-07-31

Terms related to this study

Keywords Provided by Researchers

  • knee replacement
  • exercise
  • online

Additional Relevant MeSH Terms

  • Knee Replacement