RECRUITING

Continuous Versus Single Injection Adductor Canal Blocks for Outpatient Total Knee Arthroplasty

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

This is a single-center pilot study to determine if an adductor canal continuous nerve block is superior to single injection nerve block following total knee arthroplasty. Investigators will randomize participants to either continuous nerve block or single injection nerve block for the adductor canal preoperatively. They will assess differences in pain (measured in numeric rating scale), opioid consumption, and physical therapy milestones from postoperative day 0 to 7.

Official Title

A Pilot Randomized Controlled Trial Assessing Pain and Opioid Outcomes Among Patients Undergoing Total Knee Arthroplasty Receiving 5-Day Outpatient Adductor Canal Continuous Versus Single Injection Blocks

Quick Facts

Study Start:2025-06-01
Study Completion:2025-12-01
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06784882

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. 1. Adult participants of at least 18 years of age
  2. 2. Undergoing a primary, unilateral, total knee arthroplasty
  3. 3. Planned single-injection adductor canal nerve block
  4. 4. Weight \> 50 kg (to minimize the risk of local anesthetic toxicity)
  1. 1. chronic opioid or tramadol use: daily oxycodone equivalents \> 20 mg for \> 4 weeks
  2. 2. neuro-muscular deficit of the surgical limb
  3. 3. moderate pain (NRS \> 3) in an anatomic location other than the surgical site
  4. 4. planned hospital admission following surgery
  5. 5. history of opioid misuse
  6. 6. those who lack capacity to complete informed consent
  7. 7. inability to contact the investigators during the treatment period, and vice versa (e.g., lack of telephone access)
  8. 8. incarceration
  9. 9. pregnancy
  10. 10. allergy to amide local anesthetics

Contacts and Locations

Study Contact

Rodney A Gabriel, MD
CONTACT
858-663-7747
ragabriel@health.ucsd.edu

Study Locations (Sites)

University of California, San Diego
La Jolla, California, 92037
United States

Collaborators and Investigators

Sponsor: University of California, San Diego

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2025-06-01
Study Completion Date2025-12-01

Study Record Updates

Study Start Date2025-06-01
Study Completion Date2025-12-01

Terms related to this study

Keywords Provided by Researchers

  • regional anesthesia
  • total knee arthroplasty
  • nerve block

Additional Relevant MeSH Terms

  • Acute Postoperative Pain
  • Surgery