RECRUITING

Sympathetic Vascular Transduction Across the Menopause Transition: Contributing Mechanisms

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The investigators aim to assess the interactions between the sympathetic nervous system and the vasculature in women across the menopause transition to better understand why aging women have a higher risk of cardiovascular disease.

Official Title

Sympathetic Vascular Transduction Across the Menopause Transition: Contributing Mechanisms

Quick Facts

Study Start:2025-07-10
Study Completion:2026-12
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06787066

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 70 Years
Sexes Eligible for Study:FEMALE
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Assigned female at birth
  2. * 18-70 years of age
  3. * Body mass index (BMI) \<30 kg/m2
  1. * Assigned male at birth
  2. * Pregnancy, breastfeeding
  3. * Body mass index ≥30 kg/m2
  4. * Oral hormonal contraception in last 6 months, history of hormone replacement therapy, oophorectomy
  5. * Current smoking/nicotine use
  6. * Increased risk of bleeding, pro-coagulant disorders, clotting disorders, anticoagulation therapy
  7. * Nerve/neurologic disease
  8. * Cardiovascular, hepatic, renal, respiratory disease
  9. * Blood pressure ≥140/90 mmHg
  10. * Diabetes, Polycystic ovarian syndrome
  11. * Communication barriers
  12. * Prescription medications

Contacts and Locations

Study Contact

Jacqueline Limberg, PhD
CONTACT
573-882-2420
limbergj@missouri.edu

Study Locations (Sites)

University of Missouri
Columbia, Missouri, 65211
United States

Collaborators and Investigators

Sponsor: University of Missouri-Columbia

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2025-07-10
Study Completion Date2026-12

Study Record Updates

Study Start Date2025-07-10
Study Completion Date2026-12

Terms related to this study

Keywords Provided by Researchers

  • Menopause
  • Sympathetic nerve activity
  • Sympathetic transduction
  • Blood flow
  • Women&#39;s health
  • Blood pressure

Additional Relevant MeSH Terms

  • Menopause