RECRUITING

Targeted Palliative Care Intervention for Patients With Metastatic Breast Cancer

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Patients with metastatic breast cancer who are approaching the end of life often experience high symptom burden and acute hospitalizations without sufficient communication with care teams about their end-of-life care wishes or the support of palliative or hospice services. The purpose of this multi-site trial is to test the efficacy of a targeted, five-session palliative care intervention designed specifically for those with poor prognosis metastatic breast cancer and their caregivers to improve communication with clinicians and the quality of end-of-life care. This study will lay the groundwork for ultimately delivering scalable, timely, and tailored palliative care interventions for patients with advanced cancer who have long disease trajectories.

Official Title

Randomized Trial of a Targeted Palliative Care Intervention for Patients With Metastatic Breast Cancer

Quick Facts

Study Start:2025-10-01
Study Completion:2030-03-31
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06795529

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * age ≥18 years
  2. * diagnosed with metastatic breast cancer
  3. * identified as at risk of death within 12 months per the Epic End-of-Life Care Index
  4. * functioning independently per an Eastern Cooperative Oncology Group performance status ≤2
  5. * receiving their cancer care at one of the participating institutions
  6. * able to complete questionnaires in English or Spanish
  1. * received outpatient palliative care visit within the last six months
  2. * enrolled in hospice services
  3. * diagnosed with a comorbid condition that impairs their ability to understand study procedures and/or consent for the trial as per the report of the oncology clinician(s)

Contacts and Locations

Study Contact

Jennifer Temel, MD
CONTACT
617-724-4000
jtemel@mgh.harvard.edu
Joseph Greer, PhD
CONTACT
617-724-4000
jgreer2@mgh.harvard.edu

Study Locations (Sites)

Massachusetts General Hospital
Boston, Massachusetts, 02465
United States
Duke University
Durham, North Carolina, 54677
United States
University of Pennsylvania
Philadelphia, Pennsylvania, 46205
United States

Collaborators and Investigators

Sponsor: Massachusetts General Hospital

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2025-10-01
Study Completion Date2030-03-31

Study Record Updates

Study Start Date2025-10-01
Study Completion Date2030-03-31

Terms related to this study

Keywords Provided by Researchers

  • palliative care
  • communication about care preferences

Additional Relevant MeSH Terms

  • Metastatic Breast Cancer