Auricular VNS Following Intracerebral Hemorrhage

Description

This study will evaluate whether non-invasive auricular vagal nerve stimulation lowers inflammatory markers, and improves outcomes following intracerebral hemorrhage.

Conditions

Intracerebral Hemorrhage

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Study Overview

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Study Details

Study overview

This study will evaluate whether non-invasive auricular vagal nerve stimulation lowers inflammatory markers, and improves outcomes following intracerebral hemorrhage.

Vagus Nerve Stimulation Following Intracerebral Hemorrhage (IHC) to Mitigate ICH-induced Inflammation and Cerebral Edema

Auricular VNS Following Intracerebral Hemorrhage

Condition
Intracerebral Hemorrhage
Intervention / Treatment

-

Contacts and Locations

Saint Louis

Washington University School of Medicine, Saint Louis, Missouri, United States, 63110

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Adult patients who present with a spontaneous supratentorial intracerebral hemorrhage (ICH) to Barnes Jewish Hospital
  • * Patients \< 18 years old
  • * Patients with a presumed traumatic etiology for their ICH, infratentorial location, ICH volume \> 60 ml or \< 10 ml, at risk of imminent death (e.g. Glasgow Coma Scale, GCS of 3 or one or more pupils unreactive), surgical intervention imminently planned (not including ventriculostomy)
  • * Patients undergoing active cancer therapy
  • * Patients with sustained bradycardia on arrival with a heart rate \< 50 beats per minute.
  • * Patients who cannot be enrolled within 48 hours of the initial bleed.

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Washington University School of Medicine,

Eric Leuthardt, MD MBA, STUDY_CHAIR, Washington University School of Medicine

Study Record Dates

2032-02-09