RECRUITING

Sensory Tests of Cigarettes for Identification of Flavors in Current Daily Smoking Adults

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

This clinical trial tests how well current daily smoking adults can identify flavors of cigarettes. Menthol cigarettes account for 31 percent of cigarettes sold in the United States. Flavors such as menthol play an important role in the start and continued use of tobacco products. Two ways users experience flavor is through smell and taste. Menthol has cooling and numbing properties that can increase perceptions of smoothness and reduce the perceived harshness of smoke. Menthol adds a taste and aroma commonly described as "minty". The effect of menthol flavoring on smoking behavior has been studied. Use of menthol cigarettes has been associated with greater nicotine dependence and is associated with both fewer quit attempts and lower odds of quit success. In 2022, the Food and Drug Administration proposed to restrict the use of menthol as a flavor in cigarettes. Menthol has already been banned in Canada, the United Kingdom and the European Union. In late 2022, a restriction on all flavored tobacco products went into effect in California (CA), prompting the tobacco industry to introduce substitute products that did not contain menthol. It is important to find out whether New York (NY) adult smokers who smoke menthol cigarettes can identify and characterize flavors in the same cigarette brand as sold in NY versus CA following the ban of menthol cigarettes in 2022.

Official Title

Sensory Evaluation of Cigarettes Claiming Removal of Menthol as a Characterizing Flavor

Quick Facts

Study Start:2025-05-28
Study Completion:2026-02-28
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06816459

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:21 Years to 55 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT
Inclusion CriteriaExclusion Criteria
  1. * Aged 21-55 years old
  2. * Current daily smoker of factory-made menthol cigarettes
  3. * General good health (assessed by self-rated health item)
  4. * Completion of Brief Smell Identification Test (B-SIT) with no identification of deficits
  1. * Daily concurrent use of other tobacco products (e.g., e-cigarettes, cigars, smokeless tobacco)
  2. * Known allergies to mint (peppermint, spearmint), menthol
  3. * Self-reported olfactory or taste deficits
  4. * Pregnant or nursing participants, as indicated by self-report
  5. * History of medications known to interfere with sense of smell
  6. * Positive diagnosis of coronavirus 2019 (COVID-19) within 10 days of enrollment
  7. * Current upper respiratory infection or sinus congestion (e.g., cold, flu, seasonal allergies) (by self report)

Contacts and Locations

Principal Investigator

Richard J O'Connor
PRINCIPAL_INVESTIGATOR
Roswell Park Cancer Institute

Study Locations (Sites)

Roswell Park Cancer Institute
Buffalo, New York, 14263
United States

Collaborators and Investigators

Sponsor: Roswell Park Cancer Institute

  • Richard J O'Connor, PRINCIPAL_INVESTIGATOR, Roswell Park Cancer Institute

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2025-05-28
Study Completion Date2026-02-28

Study Record Updates

Study Start Date2025-05-28
Study Completion Date2026-02-28

Terms related to this study

Additional Relevant MeSH Terms

  • Cigarette Smoking-Related Carcinoma