RECRUITING

Effects of Body Composition on Vascular Health in Females with a Healthy Body Weight

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Most of the time, body weight is evaluated by looking at the ratio of your weight to your height. This measurement is called body mass index or BMI. However, BMI does not account for what your body is actually made up of (e.g., body fat versus muscle), which may be more important for determining cardiovascular disease risk. The investigators aim to understand vascular health in females with a "healthy" BMI with differing amounts of body fat and muscle mass. We will have participants come to the lab for two different study visits. At one visit, participants will eat a meal high in fat, and at the other visit, participants will undergo a stress task.

Official Title

Resting Indicators of Vascular Health and Cardiovascular Reactivity in Females with "Normal-Weight Obesity"

Quick Facts

Study Start:2024-09-01
Study Completion:2025-12
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06818500

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 50 Years
Sexes Eligible for Study:FEMALE
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT
Inclusion CriteriaExclusion Criteria
  1. * You are 18-50 years old
  2. * Your biological sex is female
  3. * BMI is in "normal" category (18.5-24.9 kg/m2) - this BMI requirement is due to our research aims
  4. * You are not pregnant or expecting to become pregnant
  5. * You are not postmenopausal
  6. * You have not been diagnosed with a cardiometabolic condition (e.g., cardiovascular disease, type 2 diabetes)
  7. * You have not been diagnosed with a chronic inflammatory condition (e.g., rheumatoid arthritis, inflammatory bowel disease).
  8. * You do not regularly take anti-inflammatory drugs (more than 2x week) or are able to temporarily suspend use of anti-inflammatory drugs.
  9. * You do not use lipid-lowering drugs (e.g., statins), glucose-lowering drugs (e.g., metformin) tobacco products, or any illicit drugs
  10. * You do not have a pacemaker.
  11. * You do not have dietary restrictions prohibiting you from eating the provided meal (e.g., vegan/vegetarian diets, gluten-free diet, relevant food allergies).
  12. * You are able to stay in the supine position in the dark for at least 10 minutes
  1. * You are not 18-50 years old
  2. * Your biological sex is not female
  3. * Your BMI is not in the "normal" category (18.5-24.9 kg/m2) - this BMI requirement is due to our research aims
  4. * You are pregnant or expecting to become pregnant (females only)
  5. * You are postmenopausal
  6. * You have been diagnosed with a cardiometabolic condition (e.g., cardiovascular disease, type 2 diabetes)
  7. * You have been diagnosed with a chronic inflammatory condition (e.g., rheumatoid arthritis, inflammatory bowel disease).
  8. * You regularly take anti-inflammatory drugs (more than 2x week) or are unable to temporarily suspend use of anti-inflammatory drugs.
  9. * You use lipid-lowering drugs (e.g., statins), glucose-lowering drugs (e.g., metformin) tobacco products, or any illicit drugs
  10. * You have a pacemaker.
  11. * You do have dietary restrictions prohibiting you from eating the provided meal (e.g., vegan/vegetarian diets, gluten-free diet, relevant food allergies).
  12. * You are unable to stay in the supine position in the dark for at least 10 minutes

Contacts and Locations

Study Contact

Bryant H Keirns, PhD
CONTACT
7652858356
bryant.keirns@bsu.edu

Study Locations (Sites)

Ball State University- Nutrition Assessment Lab
Muncie, Indiana, 47303
United States

Collaborators and Investigators

Sponsor: Ball State University

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2024-09-01
Study Completion Date2025-12

Study Record Updates

Study Start Date2024-09-01
Study Completion Date2025-12

Terms related to this study

Keywords Provided by Researchers

  • BMI
  • Stress
  • Healthy BMI

Additional Relevant MeSH Terms

  • Normal-weight Obesity
  • BMI
  • Stress