RECRUITING

Evaluation of Empagliflozin vs Standard Care in Veterans With Prediabetes

Conditions

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Prediabetes effects 96 million people 18 years of age or older. It is important to identify treatment options to slow or prevent progression to diabetes. It is also critical to assess the potential of medications like sodium glucose transporter 2 inhibitors to reduce the risk of cardiovascular events and kidney complications, both common and costly complications of diabetes. This is a 12-week, open-label pilot feasibility study assessing the use of empagliflozin in prediabetes.

Official Title

Sodium-glucose Transporter 2 Inhibitor Use in Pre-diabetes: Initial Evaluation in Veterans

Quick Facts

Study Start:2025-03
Study Completion:2026-06
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06828731

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:35 Years to 60 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT
Inclusion CriteriaExclusion Criteria
  1. * Age 35 to 60 years at time of enrollment
  2. * Able to read and speak English
  1. * Diagnosis of diabetes (type 2 or type 1)
  2. * Contraindication to SGLT2i medication per medication labeling, prior adverse reaction to SGLT2i medication, or received SGLT2i medication within the 6 months prior to enrollment
  3. * Currently prescribed an antihyperglycemic agent approved for treatment of type 2 diabetes or taking any FDA-approved weight loss agent or over-the-counter supplement promoted for weight loss
  4. * Veterans unable to complete informed consent process (Veterans with impaired decision-making ability or who require use of a legally authorized representative)
  5. * Women who are pregnant or may become pregnant
  6. * Veterans with neurogenic bladder, indwelling catheter, or urinary tract infection within the previous 12 months requiring hospitalization or emergency department visit

Contacts and Locations

Study Contact

Beth Greck, PharmD
CONTACT
(828) 298-7911
beth.greck@va.gov

Study Locations (Sites)

Charles George VA Medical Center
Asheville, North Carolina, 28805
United States

Collaborators and Investigators

Sponsor: Charles George VA Medical Center

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2025-03
Study Completion Date2026-06

Study Record Updates

Study Start Date2025-03
Study Completion Date2026-06

Terms related to this study

Additional Relevant MeSH Terms

  • Prediabetes