Acute Radiation Dermatitis After Adjuvant Radiotherapy for Breast Cancer Patients With the Use of Silver-Plated Technology

Eligibility Criteria

• 1. ECOG ≤ 2
• 2. Male or female patients with breast cancer or breast carcinoma in situ who are recommended to receive adjuvant radiotherapy to the breast +/- regional lymph nodes or are planned to receive adjuvant radiotherapy to the chest wall and regional lymph nodes over 3 to 4 weeks.
• 3. Patients who will receive all of their RT at Magee Women's Hospital.
• 4. Agreeable to use of SPT dressing as directed (changing once weekly during RT and the additional 2 weeks following completion of RT).
• 5. Agreeable that any normal or physician recommended skin care regimen is to be used 1 hour prior to use of SPT dressing.
• 6. Agreeable to completion of assessments and skin checks and in person follow up at about 1 month following completion of RT.
• 7. Must have the ability to understand and the willingness to sign a written informed consent document.
• 1. Prior RT to the breast +/- regional lymph nodes or prior RT to the chest wall and regional lymph nodes.
• 2. Contraindication to the application of SPT dressing (e.g. allergy).
• 3. Pregnancy/lactation or women of childbearing potential who are unable or unwilling to use adequate contraception during RT.
• 4. Planned RT course \>4 weeks or \<3 weeks.
• 5. Active connective tissue disorders/collagen vascular disease, specifically dermatomyositis with a CPK level above normal or with an active skin rash in the area that will receive RT, systemic lupus erythematosis, or scleroderma.
• 6. Medical, psychiatric or other condition that would prevent the patient from receiving the protocol therapy or providing informed consent.
• 7. Known sensitivity or allergy to silver or nylon.