RECRUITING

Bleeding Patterns in Sequential and Continuous Progesterone Supplementation in Adolescents With Turner Syndrome

Description

This is a single-site open label non-randomized study comparing effects of sequential versus continuous use of progesterone supplementation amongst Turner Syndrome (TS) patients with primary ovarian insufficiency (POI) prescribed hormone replacement therapy (HRT).

Conditions

Turner SyndromePrimary Ovarian Insufficiency (Poi)
Talk to us

Related Conditions:

Turner SyndromePrimary Ovarian Insufficiency (Poi)

Study Overview

On this page

Study Details

Study overview

This is a single-site open label non-randomized study comparing effects of sequential versus continuous use of progesterone supplementation amongst Turner Syndrome (TS) patients with primary ovarian insufficiency (POI) prescribed hormone replacement therapy (HRT).

Bleeding Patterns in Sequential and Continuous Progesterone Supplementation in Adolescents With Turner Syndrome: A Non-randomized Prospective Trial (The BOOST Study)

Bleeding Patterns in Sequential and Continuous Progesterone Supplementation in Adolescents With Turner Syndrome

Condition
Turner Syndrome
Intervention / Treatment

-

Contacts and Locations

Kansas City

Children's Mercy Hospital, Kansas City, Missouri, United States, 64108

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Diagnosis of Turner Syndrome and Primary Ovarian Insufficiency.
  • * Prescribed adult dosing\* of transdermal or oral estradiol for estrogen replacement therapy.
  • * Have achieved menarche.
  • * Disclosure of sexual activity and desire for contraception.
  • * Having a levonorgestrel-releasing intrauterine device or etonogestrel arm implant in place.
  • * Having received depot medroxyprogesterone within one year prior to study recruitment.
  • * Non-English or non-Spanish speaking.

Ages Eligible for Study

12 Years to 20 Years

Sexes Eligible for Study

FEMALE

Accepts Healthy Volunteers

No

Collaborators and Investigators

Children's Mercy Hospital Kansas City,

Tazim Dowlut-McElroy, M.D., M.S., PRINCIPAL_INVESTIGATOR, Children's Mercy Kansas City

Study Record Dates

2026-07-31