RECRUITING

Treating Word Finding Difficulties in Traumatic Brain Injury With High Definition Transcranial Direct Current Stimulation

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The purpose of the study is to test whether low level electric stimulation, called transcranial Direct Current Stimulation (tDCS), on the part of the brain (i.e., pre-supplementary motor area) thought to aid in memory will improve verbal retrieval in civilian (non-military, non-veteran) participants with histories of traumatic brain injuries. The primary outcome measures are neuropsychological assessments of verbal retrieval, and the secondary measures are neuropsychological assessments of other cognitive abilities and electroencephalography (EEG) measures. Additionally, the study will examine the degree to which baseline assessments of cognition, concussion history, structural brain imaging, and EEG predict responses to treatment over time, both on assessments administered within the intervention period and at follow-up.

Official Title

Using High Definition Transcranial Direct Current Stimulation to Treat Verbal Retrieval Deficits Secondary to Chronic Traumatic Brain Injury (HDtDCS-CTBI)

Quick Facts

Study Start:2024-12-01
Study Completion:2025-12-31
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06840808

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 85 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. Age 18 years or older
  2. Willing and able to provide informed consent
  3. Able to understand and follow study procedures
  4. Stable medical condition
  1. * an implanted/electronic device, such as a pacemaker, metallic cranial or intracranial implant (e.g., ventriculoperitoneal shunt), or a neurostimulator (e.g., vagus nerve stimulator, spinal stimulator, deep brain stimulator, etc.).
  2. * skull defects
  3. * a history of a psychological or neurological disorder, including, dementia of any type, epilepsy or other seizure disorders, post-traumatic stress disorder, brain tumor, present drug abuse, stroke, blood vessel abnormalities in the brain, Parkinson's disease, Huntington's disease, or multiple sclerosis.
  4. * inability to give informed consent
  5. * currently pregnant
  6. * not a native English speaker

Contacts and Locations

Study Contact

Ashna Adhikari, MS
CONTACT
469-708-4925
ashna.adhikari@utdallas.edu
Jill Ritter, BS
CONTACT
469-708-4925
jill.ritter@utdallas.edu

Principal Investigator

John Hart, MD
PRINCIPAL_INVESTIGATOR
The University of Texas at Dallas

Study Locations (Sites)

The University of Texas at Dallas
Richardson, Texas, 75080
United States

Collaborators and Investigators

Sponsor: The University of Texas at Dallas

  • John Hart, MD, PRINCIPAL_INVESTIGATOR, The University of Texas at Dallas

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2024-12-01
Study Completion Date2025-12-31

Study Record Updates

Study Start Date2024-12-01
Study Completion Date2025-12-31

Terms related to this study

Keywords Provided by Researchers

  • electroencephalography
  • transcranial direct current stimulation
  • Cognition

Additional Relevant MeSH Terms

  • Traumatic Brain Injury
  • Cognitive Change
  • Word Finding Difficulty
  • Acquired Brain Injury