RECRUITING

NE3107 in Adults With Long COVID

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Long COVID is a condition where debilitating symptoms can persist for months after a COVID-19 infection. This study aims to evaluate the effects of NE3107 on several neurological symptoms reported in people with Long COVID including difficulty concentrating or remembering things ("brain fog") and fatigue. Researchers will compare NE3107 to a placebo (a look-alike substance that contains no drug) to see if NE3107 works to treat neurocognitive and fatigue symptoms of long COVID. Participants will: * Take NE3107 or a placebo twice daily for 84 days * Visit the clinic 5 times for checkups and tests and have a follow up phone call

Official Title

A Double-blind, Randomized Study to Evaluate the Efficacy and Safety of Bezisterim (NE3107) in Adults With Long COVID

Quick Facts

Study Start:2025-04
Study Completion:2026-01
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06847191

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 64 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT
Inclusion CriteriaExclusion Criteria
  1. * 18 years to 64 years of age
  2. * diagnosed with Long COVID with symptoms of fatigue and brain fog for at least 3 months
  3. * agree to use birth control measures
  4. * provide voluntary consent
  5. * willing to allow blood collection
  6. * pass all screening tests and procedures
  1. * has received a COVID-19 vaccination within 30 days
  2. * previous admission to the intensive care unit for COVID-19
  3. * medical history of major mental or physical illness prior to COVID-19 infection

Contacts and Locations

Study Contact

Penelope Markham, PhD
CONTACT
pmarkham@bioviepharma.com

Study Locations (Sites)

Clinical Trial Site
San Francisco, California, 94110
United States
Clinical Trial Site
Jacksonville, Florida, 32258
United States
Clinical Trial Site
Silver Spring, Maryland, 20904
United States
Clinical Trial Site
Farmington Hills, Michigan, 48334
United States

Collaborators and Investigators

Sponsor: BioVie Inc.

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2025-04
Study Completion Date2026-01

Study Record Updates

Study Start Date2025-04
Study Completion Date2026-01

Terms related to this study

Keywords Provided by Researchers

  • COVID-19
  • Neurocognition
  • Fatigue
  • Post-exertional malaise
  • Sleep
  • SARS-CoV-2
  • Brain fog

Additional Relevant MeSH Terms

  • Long COVID