Tailored Electronic Intervention to Improve Therapy in a Diverse Cohort of Patients with Heart Failure

Description

Recent medical guidelines for the management of heart failure (HF) have established a combination of specific classes of medications as the best treatment for patients with heart failure with reduced ejection fraction (HFrEF). However, studies have shown that these medications, known together as guideline-directed medical therapy (GDMT), are not being used in clinical practice less often than they could be. Several tools to promote broader use of these treatments (including patient checklists) have shown promise for increasing use of GDMT. However, these tools have not been broadly implemented within large health systems. The goal of this study is to see if using these tools broadly within cardiology clinics will increase the use of GDMT. This study is important because it could help improve the use of GDMT, which may lead to improved patient care and outcomes.

Conditions

Heart Failure

Study Overview

Study Details

Study overview

Recent medical guidelines for the management of heart failure (HF) have established a combination of specific classes of medications as the best treatment for patients with heart failure with reduced ejection fraction (HFrEF). However, studies have shown that these medications, known together as guideline-directed medical therapy (GDMT), are not being used in clinical practice less often than they could be. Several tools to promote broader use of these treatments (including patient checklists) have shown promise for increasing use of GDMT. However, these tools have not been broadly implemented within large health systems. The goal of this study is to see if using these tools broadly within cardiology clinics will increase the use of GDMT. This study is important because it could help improve the use of GDMT, which may lead to improved patient care and outcomes.

Tailored Electronic Intervention to Improve Therapy in a Diverse Cohort of Patients with Heart Failure

Tailored Electronic Intervention to Improve Therapy in a Diverse Cohort of Patients with Heart Failure

Condition
Heart Failure
Intervention / Treatment

-

Contacts and Locations

Atlanta

Emory Saint Joseph's Hospital, Atlanta, Georgia, United States, 30308

Atlanta

Emory University Hospital Midtown, Atlanta, Georgia, United States, 30308

Atlanta

Emory University Hospital, Atlanta, Georgia, United States, 30322

Johns Creek

Emory Johns Creek Hospital, Johns Creek, Georgia, United States, 30097

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Ejection fraction (EF) less than or equal to 40% by echocardiogram performed in the prior 18 months
  • * Diagnosis of heart failure
  • * Heart failure (HF) etiology for which GDMT is not indicated: including hypertrophic or restrictive cardiomyopathy (e.g. amyloid cardiomyopathy), constrictive pericarditis, or complex congenital heart disease
  • * End-stage HF requiring continuous inotrope infusion, heart transplant, or left ventricular assist device
  • * Estimated glomerular filtration rate (eGFR) \< 15 mL/min/1.73m\^2
  • * Any conditions other than HF that are likely to alter the patient's status over 6 months, indicated by active hospice status

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Emory University,

Neal W Dickert, MD, PhD, PRINCIPAL_INVESTIGATOR, Emory University

Study Record Dates

2026-06