Mechanisms of Uterine Fluid Absorption During Early Pregnancy ( ELF Study)

Description

The researchers are evaluating mechanisms of uterine fluid absorption during early pregnancy

Conditions

Endometriosis, Endometrioma

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Study Overview

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Study Details

Study overview

The researchers are evaluating mechanisms of uterine fluid absorption during early pregnancy

Mechanisms of Uterine Fluid Absorption During Early Pregnancy

Mechanisms of Uterine Fluid Absorption During Early Pregnancy ( ELF Study)

Condition
Endometriosis
Intervention / Treatment

-

Contacts and Locations

Baltimore

Johns Hopkins Hospital, Baltimore, Maryland, United States, 21287

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • 1. Subject must be a healthy woman between the ages of 18 and 45 years.
  • 2. Women with diagnosed endometriosis or infertility (cases).
  • 3. Women without a diagnosis of endometriosis or infertility (controls).
  • 4. Subject must have regular menstrual cycles.
  • 5. Subject must have a body mass index (BMI) between 18 and 40.
  • 6. Subject must be or have been sexually active or have had a previous vaginal exam that used a speculum.
  • 7. Subject must be able to understand and provide consent to procedures and use/disclosure of protected health information.
  • 8. No history of Chlamydia trachomatis, Mycoplasma genitalium, Neisseria gonorrhoeae, hepatitis B, and HIV.
  • 9. For IVF study subjects, a minimum endometrial thickness of 7mm at the time of sample collection.
  • 1. Pregnant women.
  • 2. Study subjects with endometrial cancer.
  • 3. Study subjects with a history of endometrial ablation.
  • 4. Study subjects with undiagnosed uterine bleeding.
  • 5. Women with reproductive diseases that affect the endometrium (such as fibroids or uterine polyps that distort endometrial cavity).
  • 6. Study subjects with an intrauterine device (IUD).

Ages Eligible for Study

18 Years to 45 Years

Sexes Eligible for Study

FEMALE

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

Johns Hopkins University,

James Segars, MD, PRINCIPAL_INVESTIGATOR, Johns Hopkins University

Bhuchitra Singh, MD, MPH, MS, MBA, PRINCIPAL_INVESTIGATOR, Johns Hopkins University

Study Record Dates

2030-02-01