RECRUITING

Acoustic Cluster Therapy (ACT) With Chemotherapy for the Treatment of Locally Advanced Pancreatic Cancer

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The purpose of the study is to assess the efficacy and safety of Acoustic Cluster Therapy (ACT) when given in addition to chemotherapy for treatment of Locally Advanced Pancreatic Cancer.

Official Title

A Phase 2 Study to Investigate the Efficacy and Safety of Acoustic Cluster Therapy With Modified FOLFIRINOX in Patients With Locally Advanced Pancreatic Cancer

Quick Facts

Study Start:2025-06-19
Study Completion:2027-07-15
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06850623

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Not deemed suitable for primary curative surgery and have radiographic and pathological disease consistent with inoperable LAPC or borderline resectable pancreatic cancer.
  2. * Suitable to receive treatment with mFOLFIRINOX according to the Investigator's assessment.
  1. Pregnancy or breastfeeding
  2. Severe psychiatric disorders
  3. Active substance abuse
  4. Unstable medical conditions
  5. Inability to comply with study requirements

Contacts and Locations

Study Contact

Chief Medical Officer
CONTACT
+47 46 86 39 89
clinical.trials@exact-tx.com

Study Locations (Sites)

HonorHealth Research Institute
Scottsdale, Arizona, 85258
United States

Collaborators and Investigators

Sponsor: EXACT Therapeutics AS

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2025-06-19
Study Completion Date2027-07-15

Study Record Updates

Study Start Date2025-06-19
Study Completion Date2027-07-15

Terms related to this study

Keywords Provided by Researchers

  • pancreatic cancer
  • PS101
  • ultrasound
  • microbubbles
  • Pancreatic Ductal Carcinoma
  • locally advanced pancreatic cancer
  • first line treatment
  • chemotherapy
  • Acoustic Cluster Therapy
  • mFOLFIRINOX

Additional Relevant MeSH Terms

  • Locally Advanced Pancreatic Adenocarcinoma