Efficacy of Selective Laser Trabeculoplasty Targeting Nasal Versus Inferior 180-degree

Description

The purpose of this study to optimize Selective Laser Trabeculoplasty (SLT) application when used in the management of open angle glaucoma (OAG)

Conditions

Open Angle Glaucoma

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Study Overview

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Study Details

Study overview

The purpose of this study to optimize Selective Laser Trabeculoplasty (SLT) application when used in the management of open angle glaucoma (OAG)

Efficacy of Selective Laser Trabeculoplasty Targeting Nasal Versus Inferior 180-degree

Efficacy of Selective Laser Trabeculoplasty Targeting Nasal Versus Inferior 180-degree

Condition
Open Angle Glaucoma
Intervention / Treatment

-

Contacts and Locations

Rochester

Mayo Clinic in Rochester, Rochester, Minnesota, United States, 55905

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Age 18 years and older
  • * Ability to comprehend the study procedures and agreement to proceed with primary SLT treatment
  • * Diagnosis of primary or secondary open angle glaucoma or glaucoma suspects with ocular hypertension
  • * Bilateral disease
  • * Pre-SLT IOP \>21 mmHg measured at least twice during patient's lifetime with or without medication
  • * Open angles with moderate to intense trabecular pigmentation
  • * Mild to moderate visual field defects (24-2 standard mean deviations better than the Swedish interactive thresholding algorithm standard of 12 dB)
  • * No adequate IOP control (low treatment compliance, substantial adverse effects with eyedrops, and at least 2 IOP measurements higher than the individualized target IOP)
  • * Unwilling or unable to give consent
  • * Unable to attend scheduled post-operative visits
  • * Previous history of either laser treatment or intraocular surgery, except for non-complicated cataract surgery (performed \>6 months before SLT)
  • * History of ocular trauma
  • * Narrow angles
  • * Retinal detachment
  • * Active iris neovascularization or active proliferative retinopathy
  • * Active uveitis
  • * Monocular patients
  • * Current use of steroids (ocular, periocular, or systemic)

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Mayo Clinic,

Arthur Sit, PRINCIPAL_INVESTIGATOR, Mayo Clinic

Study Record Dates

2025-12-17