Effects of Ultra Processed Food on Intestinal Energy Harvest

Description

Ultra processed food is everywhere in modern society and may contain multiple ingredients that affect the way participants' bodies store energy. Some studies have shown that eating a diet high in ultra processed foods leads to weight gain, but these foods have not been studied enough to understand why. Recently, the gut microbiome has become a potential way to measure energy balance in the human body; this is done by measuring how many calories are in the stool. The investigators propose to test a very high ultra-processed food diet where 80% of calories are coming from ultra processed food and a low ultra processed food diet where 20% of the calories are coming from ultra processed food. This study will compare stool sample energy content of the two diets.

Conditions

Obesity and Overweight

Study Overview

Study Details

Study overview

Ultra processed food is everywhere in modern society and may contain multiple ingredients that affect the way participants' bodies store energy. Some studies have shown that eating a diet high in ultra processed foods leads to weight gain, but these foods have not been studied enough to understand why. Recently, the gut microbiome has become a potential way to measure energy balance in the human body; this is done by measuring how many calories are in the stool. The investigators propose to test a very high ultra-processed food diet where 80% of calories are coming from ultra processed food and a low ultra processed food diet where 20% of the calories are coming from ultra processed food. This study will compare stool sample energy content of the two diets.

Effects of Ultra Processed Food on Intestinal Energy Harvest

Effects of Ultra Processed Food on Intestinal Energy Harvest

Condition
Obesity and Overweight
Intervention / Treatment

-

Contacts and Locations

New York

Columbia University Irving Medical Center, New York, New York, United States, 10032

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * BMI 30-40kg/m2
  • * weight stable
  • * able to download app and willing to use it for duration of study
  • * does own grocery shopping
  • * otherwise healthy
  • * pregnancy
  • * history of or planned bariatric surgery
  • * history of anti obesity medications

Ages Eligible for Study

25 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Columbia University,

Kathryn J Whyte, PhD, MS, RDN, PRINCIPAL_INVESTIGATOR, Columbia University

Study Record Dates

2026-08