RECRUITING

Brain and Behavior Influences on Obesity Development From Infancy Through Childhood

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The investigators project, RESONATE, aims to investigate why some children develop obesity. To do this it uses data on eating and eating-related behaviors, genetic and environmental factors, and brain structure and function. This data is collected in a sub-sample of RESONANCE, a large study of families of children from infancy through childhood. The results will lay foundations for the development of early interventions to prevent or treat obesity.

Official Title

Early Brain Development and Child Nutrition and Obesity

Quick Facts

Study Start:2024-12-02
Study Completion:2029-03-31
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06861868

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:7 Years to 12 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:CHILD
Inclusion CriteriaExclusion Criteria
  1. * Participants from the RESONANCE cohort are eligible if the participant will reach 7-12 years of age during the proposed project period and have no food allergies.
  1. * Exclusion criteria for RESONANCE include:
  2. 1. In utero exposure to alcohol, cigarette, or illicit substances;
  3. 2. First trimester fetal US abnormalities;
  4. 3. Complicated pregnancy (e.g., pre-eclampsia);
  5. 4. Complicated delivery, including APGAR scores less than 8 and/or neonatal intensive care unit (NICU) admission;
  6. 5. History of neurological (e.g., epilepsy), psychiatric (e.g., anxiety or depression requiring treatment with medication) or developmental disorder (e.g., autism spectrum disorder (ASD), dyslexia);
  7. 6. Contraindications for MRI including metal in the body, claustrophobia.

Contacts and Locations

Study Contact

Susan Carnell, PhD
CONTACT
410-955-7192
susan.carnell@jhmi.edu
Viren D'Sa, MD
CONTACT
312-371-4178
viren_dsa@brown.edu

Principal Investigator

Susan Carnell, PhD
PRINCIPAL_INVESTIGATOR
Johns Hopkins University

Study Locations (Sites)

Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
Baltimore, Maryland, 21205
United States
Johns Hopkins University School of Medicine
Baltimore, Maryland, 21287
United States
Rhode Island Hospital
Providence, Rhode Island, 02903
United States
University of Washington
Seattle, Washington, 98109
United States

Collaborators and Investigators

Sponsor: Johns Hopkins University

  • Susan Carnell, PhD, PRINCIPAL_INVESTIGATOR, Johns Hopkins University

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2024-12-02
Study Completion Date2029-03-31

Study Record Updates

Study Start Date2024-12-02
Study Completion Date2029-03-31

Terms related to this study

Keywords Provided by Researchers

  • obesity
  • overweight
  • pediatric
  • eating behavior
  • appetite
  • neuroimaging
  • magnetic resonance imaging
  • brain development

Additional Relevant MeSH Terms

  • Obesity and Overweight