RECRUITING

Effect of Exercise and Heat Stress on Acute Cardiometabolic Adaptations in Healthy Young Adults

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Life in space is completely void of physical and environmental stress. It is well known that living things need regular physical stress (e.g. exercise) to remain strong, functional and healthy. More and more research is showing that regular environmental stress, for example heat and hypoxia, can further improve physical health. Astronauts aboard the international space station (ISS) exercise for 1-2 hours every day to avoid physical deconditioning that would otherwise cause them to age rapidly in space. Although physical exercise is very effective in remedying this deconditioning, today's astronauts still have physiological changes that indicate accelerated aging. This is a cause for concern given NASA's priority to travel to mars within the next decade; a mission that will require at least double the duration in space for our astronauts. The investigators think that the complete absence of environmental stress, i.e., heat, may be contributing to the accelerated aging that occurs during spaceflight. Our study will assess the health effects of adding heat stress to exercise that could be performed in space by astronauts. The goal is to inform best practice for astronauts to avoid physical deconditioning during long-duration spaceflight. This information will also be relevant to life on earth as spaceflight is a model of inactivity here on earth. Therefore, the potential benefits of adding heat stress will likely translate to life in space and on earth.

Official Title

Does Heat Stress Improve the Acute Metabolic and Cardiovascular Adaptations to Exercise

Quick Facts

Study Start:2025-03-01
Study Completion:2026-05-21
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06872762

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 50 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT
Inclusion CriteriaExclusion Criteria
  1. Age 18 years or older
  2. Willing and able to provide informed consent
  3. Able to understand and follow study procedures
  4. Stable medical condition
  1. * smokers
  2. * bronchial asthma
  3. * chronic obstructive pulmonary disease
  4. * obese
  5. * alcoholism
  6. * requiring daily medications that may effect responses to exercise,
  7. * anti-arrhythmogenics
  8. * inhalers
  9. * history of cardiovascular, respiratory, neurological, skeletal muscle disease
  10. * irregular/absent menstrual cycle (females)
  11. * unexpected responses to pre-experimental exercise tests
  12. * previous diagnosis of heat stroke

Contacts and Locations

Study Contact

Travis Gibbons, PhD
CONTACT
928-523-4002
travis.gibbons@nau.edu

Study Locations (Sites)

Northern Arizona University
Flagstaff, Arizona, 86011
United States

Collaborators and Investigators

Sponsor: Northern Arizona University

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2025-03-01
Study Completion Date2026-05-21

Study Record Updates

Study Start Date2025-03-01
Study Completion Date2026-05-21

Terms related to this study

Keywords Provided by Researchers

  • exercise
  • heat strain
  • glucose tolerance test
  • arterial compliance

Additional Relevant MeSH Terms

  • Exercise
  • Heat Strain
  • Control Condition