RECRUITING

Psychobiological Responses Following Exercise and Brain Stimulation

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Anxiety disorders are the most common mental health diagnosis in the US; 19.1% of U.S. adults (23.4% for females and 14.3% for males). In addition, the Global Burden of Disease study (2010) found that anxiety disorders were the sixth leading cause of disability (years of life lived with disability). These debilitating disorders are characterized by excessive worry and fear about everyday situations, and physical symptoms including restlessness, being easily fatigued, difficulty concentrating, irritability, muscle tension, or sleep disturbance. Furthermore, anxiety is linked to other mental disorders including depression and substance abuse; is associated with cardiovascular disease risk factors and a higher rate of cardiovascular disease; and is related to premature mortality. These data have led to the investigation of a breadth of plausible treatments for anxiety, including medications and psychotherapy. However, likely due to the breadth of complex mechanisms involved in the pathophysiology of anxiety disorders and the unfavorable side effects of various medications, a considerable number of individuals do not have a satisfactory response to these treatments. This has led investigators to examine plausible novel interventions to alleviate anxiety and its symptoms.

Official Title

Psychobiological Responses Following Exercise and Brain Stimulation

Quick Facts

Study Start:2025-03
Study Completion:2025-12
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06874595

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 50 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT
Inclusion CriteriaExclusion Criteria
  1. * Healthy adults
  2. * aged 18 to 50
  3. * consent and complete a Physical Activity Readiness Questionnaire (PAR-Q)
  4. * be free from any neurological or psychiatric disorder
  5. * not be taking any medication that could affect the central nervous system
  6. * not have any contraindication for HD-tDCS (i.e. not having metal implanted in the head, pacemaker, medical bumps, seizures, lesions on the scalp or head ) or for bioelectrical impedance (i.e., electronic medical implant, such as a pacemaker or implantable cardioverter defibrillator, and limb amputation)
  7. * not be regular users of tobacco products (cigarettes, cigars, chewing tobacco)
  8. * not consume an average of more than ten alcoholic beverages per week
  1. * Individuals who do not meet the PAR-Q screening criteria for participation in moderate physical activity will be excluded from participating in this study
  2. * women who are pregnant will be exclude from this study

Contacts and Locations

Study Contact

Edmund Acevedo
CONTACT
(804) 814-4355
eoacevedo@vcu.edu
Monique Morton
CONTACT
804-828-1948
mortonmy@vcu.edu

Principal Investigator

Edmund Acevedo
PRINCIPAL_INVESTIGATOR
Virginia Commonwealth University

Study Locations (Sites)

Virginia Commonwealth University
Richmond, Virginia, 23298
United States

Collaborators and Investigators

Sponsor: Virginia Commonwealth University

  • Edmund Acevedo, PRINCIPAL_INVESTIGATOR, Virginia Commonwealth University

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2025-03
Study Completion Date2025-12

Study Record Updates

Study Start Date2025-03
Study Completion Date2025-12

Terms related to this study

Keywords Provided by Researchers

  • Exercise and Brain Stimulation

Additional Relevant MeSH Terms

  • Psychological