RECRUITING

Early Avocado Exposure on Development and the Gut Microbiome in American Hispanic Infants

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The goal of this clinical trial is to learn if daily avocado intake can improve growth and brain and gut health in infants. The main questions it aims to answer are: Does daily eating of avocados change which microbes live in the infant's gut? Does daily avocado intake improve infant motor skills and cognitive development? Researchers will compare avocado intake to standard of care (no or limited avocado intake) to see if regular avocado intake from 6-12 months of life influences gut and brain health. Participating mothers/guardians and their infants will: Parents will provide avocado or no avocado to their infant every day for 6 months starting around 6 months of infant age. Parents will allow study staff to visit participant homes to collect data via surveys and observations and measure infant growth. Parents will swab soiled infant diapers for gut microbe measures. Parents will keep a diary of the infant's avocado consumption and acceptance of the food. Parents will record their infant's dietary intake

Official Title

Guac & Grow: Early Avocado Exposure on Development and the Gut Microbiome in American Hispanic Infants

Quick Facts

Study Start:2025-08-05
Study Completion:2027-12-31
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06876935

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:3 Months to 6 Months
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:CHILD
Inclusion CriteriaExclusion Criteria
  1. * 4-6-month-old Hispanic/Latine, non-preterm (\>37 weeks gestation) singleton infants
  2. * Infants born to mothers 18 years and older while pregnant
  3. * Parents speak English and/or Spanish
  4. * Families willing to begin feeding infants avocado around 6 months of age or when the infant is ready for solids for a total of 6 months
  5. * Family history of food or latex allergies will be evaluated as avocado is a latex fruit and can cause allergic responses. If either mom or dad is allergic to avocado, physician clearance for infant participation will be needed.
  6. * At least one caregiver in the home must have at least an 8th-grade education level
  1. * Infants with growth, chromosomal, or genetic abnormality, developmental and cognitive impairments, or severe comorbidity that could impact growth and development
  2. * Infants born with congenital abnormalities or developmental delays
  3. * Infant birth weights \<2500 g or \>4000 g
  4. * Infants introduced to solid foods prior to 3 months of age
  5. * Biological mothers with known substance use during pregnancy (alcohol, tobacco, marijuana, or illegal drugs), or who experienced a high-risk pregnancy (e.g., preeclampsia, diabetes-Types 1 and 2 and gestational, HIV, etc.)

Contacts and Locations

Study Contact

Corrie M Whisner, PhD
CONTACT
602-496-3348
cwhisner@asu.edu
Rachel Tribby, BS
CONTACT
rtribby@asu.edu

Principal Investigator

Corrie M Whisner, PhD
PRINCIPAL_INVESTIGATOR
Arizona State University

Study Locations (Sites)

College of Health Solutions
Phoenix, Arizona, 85004
United States

Collaborators and Investigators

Sponsor: Arizona State University

  • Corrie M Whisner, PhD, PRINCIPAL_INVESTIGATOR, Arizona State University

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2025-08-05
Study Completion Date2027-12-31

Study Record Updates

Study Start Date2025-08-05
Study Completion Date2027-12-31

Terms related to this study

Keywords Provided by Researchers

  • avocado
  • infants
  • complimentary feeding
  • growth
  • development
  • gut microbiome
  • neurocognitive
  • brain health

Additional Relevant MeSH Terms

  • Gut Microbiome
  • Neurocognitive Correlates of Eating Habits
  • Infant Growth