RECRUITING

Building Undergraduate Coping & Knowledge for Stress-Resilience

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Nearly 60% of college students use alcohol and 30% binge drink monthly. This is alarming given that heavy alcohol use is linked to serious detrimental outcomes. Despite various prevention and intervention strategies, heavy alcohol use has remained relatively stable over the past decade. Individual differences in stress response connote risk for alcohol use disorder. Anxiety sensitivity (AS) and intolerance of uncertainty (IU) are two key cognitive vulnerabilities that can hinder resilience by amplifying stress responses and promoting maladaptive coping strategies, such as alcohol use. Effective stress management is a cornerstone of resilience. The Intervention for Managing Psychological Responding to Overwhelming Emotions (IMPROVE) targets AS and IU, key barriers to resilience, by modifying cognitive processes that amplify stress and negative affect. In this study, undergraduate students who engage in heavy drinking behaviors and experience elevated anxiety symptoms will be randomized to IMPROVE or a control health promotion intervention (N=20 per arm). All participants will complete daily ecological momentary assessments (EMA) delivered to participants' mobile phones to capture real-world alcohol use before, during, and after the intervention. The investigators will evaluate the feasibility and acceptability of IMPROVE (Aim 1). The investigators will also include a multimodal battery of self-report and objective lab-based measures of AS and IU involving startle eyeblink potentiation and event-related potentials via electromyography (EMG) and electroencephalography (EEG). This will allow the investigators to examine whether IMPROVE changes IU and AS, and to assess if changes in these targets are associated with changes in alcohol use (Aim 2).

Official Title

A Resilience-Based Intervention for Reducing Problematic Alcohol Use in College Populations

Quick Facts

Study Start:2025-02-01
Study Completion:2027-01-01
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06885320

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * report elevated psychological distress (i.e., Kessler Psychological Distress Scale scores \>12)
  2. * engage in heavy drinking behaviors (i.e., 15 drinks per week for biological males and 8 drinks per week for biological females)
  3. * age 18 or older
  4. * can read and comprehend English
  5. * has access to a smartphone
  1. * limited mental competency/inability to give informed consent
  2. * current comorbid moderate to severe substance use disorder other than nicotine

Contacts and Locations

Study Contact

Nicholas Allan, PhD
CONTACT
614-814-1299
nicholas.allan@osumc.edu
Sarah Millisor Irvin, MSc
CONTACT
614-814-1318
sarah.irvin@osumc.edu

Study Locations (Sites)

The Ohio State University Department of Psychiatry and Behavioral Health
Columbus, Ohio, 43210
United States

Collaborators and Investigators

Sponsor: Ohio State University

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2025-02-01
Study Completion Date2027-01-01

Study Record Updates

Study Start Date2025-02-01
Study Completion Date2027-01-01

Terms related to this study

Keywords Provided by Researchers

  • alcohol
  • transdiagnostic
  • anxiety
  • college students

Additional Relevant MeSH Terms

  • Alcohol Use
  • College Drinking
  • Anxiety