RECRUITING

Pelvic Vein Quantitative Flow Characterization Using 2D and 4D Flow MRI

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The purpose of the study is to quantitatively characterize the flow in the pelvic venous structures using 2D and 4D flow MRI with the objective of establishing physiologic and pathologic parameters for downstream computational fluid dynamics analysis. Arm 1: To establish the baseline flow characteristics of the iliac veins in patients with no imaging evidence of iliac venous disease. Arm 2: To assess the flow characteristics of the iliac veins in patients with left iliac vein compression syndrome (a.k.a. May-Thurner syndrome). Arm 3: To assess the flow characteristics of the iliac veins in patients status post iliac stent placement.

Official Title

Pelvic Vein Quantitative Flow Characterization Using 2D and 4D Flow MRI

Quick Facts

Study Start:2025-04-01
Study Completion:2027-01-01
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06888024

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 89 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. Age 18 years or older
  2. Willing and able to provide informed consent
  3. Able to understand and follow study procedures
  4. Stable medical condition
  1. * History of pelvic or iliac venous disease or intervention
  2. * Contraindication to MRI examination
  3. * Prisoners
  4. * Subjects ≤ 18 years of age
  5. * Pregnant women
  6. * Adults unable to provide informed consent

Contacts and Locations

Study Contact

Sara Schiller, MPH, CCRP
CONTACT
774-525-1517
sara.schiller1@umassmed.edu

Principal Investigator

Ningcheng Li, MD
PRINCIPAL_INVESTIGATOR
UMass Chan Medical School

Study Locations (Sites)

University of Massachusetts
Worcester, Massachusetts, 01655
United States

Collaborators and Investigators

Sponsor: Ningcheng Peter Li

  • Ningcheng Li, MD, PRINCIPAL_INVESTIGATOR, UMass Chan Medical School

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2025-04-01
Study Completion Date2027-01-01

Study Record Updates

Study Start Date2025-04-01
Study Completion Date2027-01-01

Terms related to this study

Keywords Provided by Researchers

  • May-Thurner Syndrome
  • Iliac Venous Disease

Additional Relevant MeSH Terms

  • May-Thurner Syndrome
  • Iliac Venous Compression