Pelvic Vein Quantitative Flow Characterization Using 2D and 4D Flow MRI

Description

The purpose of the study is to quantitatively characterize the flow in the pelvic venous structures using 2D and 4D flow MRI with the objective of establishing physiologic and pathologic parameters for downstream computational fluid dynamics analysis. Arm 1: To establish the baseline flow characteristics of the iliac veins in patients with no imaging evidence of iliac venous disease. Arm 2: To assess the flow characteristics of the iliac veins in patients with left iliac vein compression syndrome (a.k.a. May-Thurner syndrome). Arm 3: To assess the flow characteristics of the iliac veins in patients status post iliac stent placement.

Conditions

May-Thurner Syndrome, Iliac Venous Compression

Study Overview

Study Details

Study overview

The purpose of the study is to quantitatively characterize the flow in the pelvic venous structures using 2D and 4D flow MRI with the objective of establishing physiologic and pathologic parameters for downstream computational fluid dynamics analysis. Arm 1: To establish the baseline flow characteristics of the iliac veins in patients with no imaging evidence of iliac venous disease. Arm 2: To assess the flow characteristics of the iliac veins in patients with left iliac vein compression syndrome (a.k.a. May-Thurner syndrome). Arm 3: To assess the flow characteristics of the iliac veins in patients status post iliac stent placement.

Pelvic Vein Quantitative Flow Characterization Using 2D and 4D Flow MRI

Pelvic Vein Quantitative Flow Characterization Using 2D and 4D Flow MRI

Condition
May-Thurner Syndrome
Intervention / Treatment

-

Contacts and Locations

Worcester

University of Massachusetts, Worcester, Massachusetts, United States, 01655

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * History of pelvic or iliac venous disease or intervention
  • * Contraindication to MRI examination
  • * Prisoners
  • * Subjects ≤ 18 years of age
  • * Pregnant women
  • * Adults unable to provide informed consent

Ages Eligible for Study

18 Years to 89 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

Ningcheng Peter Li,

Ningcheng Li, MD, PRINCIPAL_INVESTIGATOR, UMass Chan Medical School

Study Record Dates

2027-01-01