Investigators are trying to find better treatments for people with HIV-1. In this clinical study, investigators want to see how well a new treatment called ISL+ULO, taken once a week, works compared to an existing treatment called BIC/FTC/TAF, which is taken every day. Investigators will check how many people still have a high level of the virus in their blood after 24 weeks. The investigators also want to understand if the new treatment, MK-8591B, is safe and how well people can handle it.
Human Immunodeficiency Virus Type 1 (HIV-1) Infection
Investigators are trying to find better treatments for people with HIV-1. In this clinical study, investigators want to see how well a new treatment called ISL+ULO, taken once a week, works compared to an existing treatment called BIC/FTC/TAF, which is taken every day. Investigators will check how many people still have a high level of the virus in their blood after 24 weeks. The investigators also want to understand if the new treatment, MK-8591B, is safe and how well people can handle it.
A Study of Islatravir (ISL) and Ulonivirine (ULO) Once Weekly (QW) in Virologically Suppressed Adults With Human Immunodeficiency Virus Type 1 (HIV-1) (MK-8591B-060)
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Zuckerberg San Francisco General Hospital and Trauma Center ( Site 4107), San Francisco, California, United States, 94110
Mills Clinical Research ( Site 4109), West Hollywood, California, United States, 90046
Georgetown University Medical Center ( Site 4106), Washington, District of Columbia, United States, 20007
Orlando Immunology Center ( Site 4103), Orlando, Florida, United States, 32803
Triple O Research Institute ( Site 4111), West Palm Beach, Florida, United States, 33407
Chatham County Health Department - Chatham CARE Center ( Site 4116), Savannah, Georgia, United States, 31401
KC CARE Health Center ( Site 4101), Kansas City, Missouri, United States, 64111
Regional Center for Infectious Diseases ( Site 4115), Greensboro, North Carolina, United States, 27401
Central Texas Clinical Research ( Site 4100), Austin, Texas, United States, 78705
Prism Health North Texas, Oak Cliff Health Center ( Site 4114), Dallas, Texas, United States, 75208
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
For general information about clinical research, read Learn About Studies.
18 Years to
ALL
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Merck Sharp & Dohme LLC,
Medical Director, STUDY_DIRECTOR, Merck Sharp & Dohme LLC
2027-09-24